University of Bern has huge a campus in Switzerland and widely known as for its contribution in top notch education and research. The contribution of University of Bern, Switzerland is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc.

1. PhD studentship opportunity: Comparative effectiveness of cervical cancer screening policies in Zambia – a mathematical modeling approach

Summary of Doctoral Project:

Under the supervision of Prof. Egger and Dr. Iskandar, the student will engage in method research, specifically, in the development of (1) a modeling framework that is amenable to various data sparsity situations and (2) a stochastic model to emulate the transmission dynamic of HIV and HPV and cervical (pre-)cancer progression. The method work will draw upon approaches from quantitative disciplines such as stochastic process, simulation modeling, and epidemiology. The student will also conduct cost-effectiveness analyses of different cervical cancer screening policies. In addition, the student is expected to liaise with project partners in Zambia, contribute to ongoing activities within IeDEA-SA, present work at international conferences and publish articles in peer-reviewed journals.

Last Application Date: Open Until Filled

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2. PhD position in machine learning, protein modeling and design

Summary of Doctoral Project:

We are looking for a PhD candidate to work in the areas of machine learning, and protein modeling and design. Research objectives include the development and implementation of deep generative models for protein design with applications in the fields of antibody therapeutics and biosensor design. The research will be carried out in the group of Thomas Lemmin of the Institute of Biochemistry and Molecular Medicine (IBMM) at the University of Bern, in Bern, Switzerland.

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3. PhD position in machine learning, protein modeling and design

Summary of Doctoral Project:

We are looking for a PhD candidate to work in the areas of machine learning, and protein modeling and design. Research objectives include the development and implementation of deep generative models for protein design with applications in the fields of antibody therapeutics and biosensor design. The research will be carried out in the group of Thomas Lemmin of the Institute of Biochemistry and Molecular Medicine (IBMM) at the University of Bern, in Bern, Switzerland.

Last Application Date: Open Until Filled

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4. PhD position in the fields of Structural and Computational Biology

Summary of Doctoral Project:

We are looking for a PhD candidate to work on an interdisciplinary project in the areas of electron cryo-tomography (cryo-ET), deep learning, and protein modeling. Research objectives include the development and implementation of deep learning models for the segmentation and structural analysis of non-discrete protein assemblies in cells imaged by cryo-ET. The research will be carried out jointly in the groups of Wanda Kukulski and Thomas Lemmin of the Institute of Biochemistry and Molecular Medicine (IBMM) at the University of Bern, in Bern, Switzerland.

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5. PhD student in Geological Sciences

Summary of Doctoral Project:

The PhD project is tailored to provide this knowledge. Accordingly, the responsibilities of the PhD student include the establishment of a database on the routing of sediment in these basins from the hillslopes through the channel network down to the valleys. The methods include a wide range of quantitative geomorphology techniques such as (i) terrestrial cosmogenic 10Be and 14C for tracing sediment and to quantify sediment storage and transport, (ii) landscape and channel surveys with UAVs (unmanned aerial vehicles such as drones) to document changes of channels and hillslopes, and (iii) the application of engineering-based models to predict the channel response to heavy precipitation events and to model sediment mobilization by debris flows.

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6. PhD student in Geological Sciences

Summary of Doctoral Project:

The institute of Geological Sciences of the University of Bern and the Swiss Federal Institute for Forest, Snow and Landscape Research WSL invite talented, motivated and excellent candidates to apply for a fully funded PhD position where the PhD student will be embedded in an interdisciplinary project including hydrologists, political scientists and economists. We focus on heavily modified landscapes in pre-Alpine areas of Switzerland where mountain streams have been channelized and engineered with check dams. We aim at exploring more natural ways of managing such drainage basins. To achieve these goals, we need a quantitative understanding of the functioning of such landscapes. We think that we can offer a fascinating project embedded in an interdisciplinary team where cutting-edge methods in quantitative geomorphology will be applied for practical use. The PhD student will be supervised by F. Schlunegger (Uni Bern) and B. McArdell (WSL), and the student will be enrolled at Uni Bern.

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7. PhD student

Summary of Doctoral Project:

The Swine Clinic in the Department of Clinical Veterinary Medicine is part of the Vetsuisse Faculty, University of Bern, Switzerland. Our core business is the education of veterinary medicine in the field of pig medicine with strong emphasis on porcine health management. In order to extend our team and to support or international research projects, we are currently offering a position as a: PhD student The research project is embedded in a larger context that focus on influenza virus infections in human and pigs. Information about the project ‘An integrative One Health network to monitor and characterize influenza A viruses circulating in the human and pig population’ can be found here: https://bit.ly/3AVH0tr The PhD student will be enrolled in the Graduate School of Cellular and Biomedical Sciences (http://www.gcb.unibe.ch) at the University of Bern. The work will include sampling in the field, epidemiological investigations, and wet-lab work.

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8. PhD Student Position: Identification of novel drug targets in American trypanosomiasis using chemoproteomics and metabolomics

Summary of Doctoral Project:

We offer a PhD project at the Institute of Biochemistry and Molecular Medicine (Prof. Jürg Gertsch, www.gertschlab.com) for a highly motivated and talented young researcher with strong interest in parasitology, biochemistry and small molecules. Making use of the highly antichagasic natural products identified in a comprehensive parasite infection screening (Salm et al., 2021, iScience, 24(4), p. 102310), we use chemical biology (natural product-derived clickable probes) to identify the underlying targets of the most antichagasic natural products, as well as metabolomics and state-of-the-art Crispr-Cas9 knockout technologies on T. cruzi established in the lab. Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite T. cruzi and mainly affects the indigenous population in Latin America.

Last Application Date: Open Until Filled

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9. PhD Position in Gut microbiota and immune system development

Summary of Doctoral Project:

The symbiotic microorganisms colonize all mucosal body surfaces of newborns and play a key role in shaping the development and maturation of immune system. In the intestine, the first vigorous immune response to colonizing bacteria after birth occurs at weaning. This response termed “weaning reaction” is critical for generating an immune memory that dictate the tolerance or the susceptibility to multiple inflammatory pathologies later in life (Al Nabhani et al., Immunity 2019, Nature Metabolism 2019). In the framework of ERC starting project, we are seeking to gain knowledge regarding the immunological and microbiological mechanisms behind the weaning reaction. We aim to assess the dietary and microbial components that influence immune memory generation and impact the susceptibility to develop both metabolic disorders and immune-mediated diseases. The successful candidate will work on the project using different transgenic germ-free and gnotobiotics mouse models and acquiring variety of techniques including flow cytometry, scRNAseq, mass spectrometry and shotgun metagenomic sequencing.

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10. PhD Position in Atmosphere Modelling

Summary of Doctoral Project:

The goal of the proposed PhD project is to extend this model to also cover the collisional regime in atmospheres with a Direct Simulation Monte Carlo module to which our existing model will be coupled. This model will be used to study atmospheres of planetary objects in our own solar system as well as in other solar systems (i.e., exoplanets). Collisional atmospheres are found on a wide variety of objects in our solar system, including Mars, Earth, Venus, Titan, and Callisto. Numerous Earth- and space-based spectroscopic and in situ measurement campaigns of planetary atmospheres within our solar system have provided us with a wealth of data that we can use to test and verify our model. For exoplanets, the first and often only way to determine the planet’s chemical composition is to observe its atmosphere. In addition, atmospheric properties such as density and temperature provide further information about the exoplanet and the environment in which it is situated. One of the main objectives here is to determine if an exoplanet might be habitable.

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11. PhD position in molecular Virology

Summary of Doctoral Project:

At the Division of Neurological Sciences, Vetsuisse Faculty, University of Bern a PhD student position is available. Our SNF-funded research project focuses on gaining a fundamental understanding of the Paramyxovirus cell-entry process and the development of next-generation multidomains neutralizing antibodies.

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12. PhD student position in ion channels in the placenta

Summary of Doctoral Project:

Our research groups (Albrecht/Peinelt) are located at the Institute for Biochemistry and Molecular Medicine (IBMM, University of Bern, Switzerland; https://www.ibmm.unibe.ch). The IBMM is a multi-disciplinary environment with state-of-the-art facilities promoting cutting-edge research. Our groups are interested in the physiology and pathophysiology of ion channels (STIM/Orai, TRP channels) and mother-child placental interactions. For a joined project (Peinelt/Albrecht), we are looking for a motivated PhD candidate who is interested in ion channels in the placenta. The candidate will work with various methods (Ca2+ imaging, electrophysiology, molecular biology, biochemistry and cellular assays) and cell lines as well as primary cells. The candidate will be able to present his/her work at national and international meetings and publish in scientific journals. We offer participation in various career promoting workshops and network events. Our PhD candidate will join the Graduate School for Cellular and Biomedical Sciences (https://www.gcb.unibe.ch/) an international and structured PhD program (English) ensuring high education quality, a friendly feedback culture, and guidance and mentorship by an individual thesis advisory committee.

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13. Postdoctoral/Senior Researcher in Modelling Transformation Pathways

Summary of Doctoral Project:

The Wyss Academy for Nature at the University of Bern’s vision is to achieve a just and sustainable world in which nature conservation and human wellbeing reinforce each other. Our goal is to bring different stakeholders together to research, co-design, and implement innovative solutions to tackle climate change, biodiversity loss, land use change and rising inequality by connecting technical, social, economic, institutional and policy innovations at the interface of nature and people. The Wyss Academy comprises four regional hubs, one each in Europe (Switzerland), South America (Peru), East Africa (Kenya), and Southeast Asia (Laos). In the framework of an interdisciplinary research project, the Professorship of Climate Scenarios for Sustainable Development and the Professorship of Political Economy and Sustainable Development at the University of Bern are inviting motivated candidates to apply for the position of a Postdoctoral/Senior Researcher in Modelling Transformation Pathways.

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14. PhD position in neuromodulation at the University Hospital of Berne

Summary of Doctoral Project:

A PhD position is available at the Division of Neurorehabilitation, Department of Neurology, Inselspital, University Hospital of Berne, Switzerland. The research group investigates brain plasticity in patients with acquired brain injury and the effects of new treatment approaches based on neurotechnology. http://www.neurologie.insel.ch/de/lehre-und forschung/forschung/researchgroups/neurorehabilitation-neuromodulation The project will use high-density EEG-based neurofeedback technology to enhance functional connectivity as new treatment approach for improving learning in heathy human subjects and patients with stroke.

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15. PhD position in Neuromodulation

Summary of Doctoral Project:

A PhD position is available at the Division of Neurorehabilitation, Department of Neurology, Inselspital, University Hospital of Berne, Switzerland. The research group investigates brain plasticity in patients with acquired brain injury and the effects of new treatment approaches based on neurotechnology. The project will use high-density EEG-based neurofeedback technology to enhance functional connectivity as new treatment approach for improving learning in heathy human subjects and patients with stroke.

Last Application Date: Open Until Filled

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16. PhD position on “Modeling the energy supply of the brain in health and disease”

Summary of Doctoral Project:

The key energy substrates of the brain are glucose and oxygen. Both are delivered to the brain via an intricate network of blood vessels. Recently, novel datasets resolving the entire vasculature of the mouse brain became available, which offer unique opportunities to study the brain’s energy supply. This requires developing and applying novel numerical methods to simulate blood flow and nutrient transport in large microvascular networks and the surrounding tissue.

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17. PhD Student Position: Role of transporters in Trypanosoma cruzi biology and as drug targets: functional, biochemical and biophysical studies

Summary of Doctoral Project:

For a jointly supervised interdisciplinary PhD project at the Institute of Biochemistry and Molecular Medicine (https://www.ibmm.unibe.ch: Profs. Jürg Gertsch and Dimitrios Fotiadis), we are looking for a highly motivated and talented young researcher with strong interest in parasitology, biochemistry and biophysics. We aim to investigate the role of specific transporters for drug discovery in Chagas disease using established Trypanosoma cruzi cellular infection assays and state-of-the-art Crispr-Cas9 knockout technologies. Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite T. cruzi and mainly affects the indigenous population in Latin America. Currently, there are no suitable drugs to treat the chronic stage of the disease and new approaches for drug discovery are needed. Specific T. cruzi transporters will be expressed heterologously in different cell systems to establish in vitro screening assays, and to produce milligram amounts for purification and biochemical and biophysical characterization.

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18. PhD position in computational modelling of asteroid collisions

Summary of Doctoral Project:

The aim of this project is to study the origin and collisional evolution of asteroids and their precursors – the planetesimals – using realistic rheological models based on advanced laboratory and space mission impact experiments. Data from the upcoming NASA DART mission impact will be used for the validation and calibration of the numerical models. The second part of the project will investigate ≈ 100 km sized objects to determine the merging criteria and fragmentation threshold as a function of their properties. These studies will be the basis for a general framework of collision outcomes, as required in planet formation models. These studies will also include investigations of possible formation scenarios of asteroid (16) Psyche, target of NASA’s ‘Psyche’ mission (scheduled to launch in August 2022). The studies will be conducted using sophisticated Smoothed Particle Hydrodynamics (SPH) simulations. The successful candidate is expected to develop a new module to model the post-impact re-accumulation process, to be included in the Bern SPH code.

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