{"id":11540,"date":"2024-05-06T23:00:52","date_gmt":"2024-05-06T23:00:52","guid":{"rendered":"https:\/\/notesbard.com\/?p=11540"},"modified":"2024-05-05T18:36:21","modified_gmt":"2024-05-05T18:36:21","slug":"09-postdoctoral-jobs-at-university-of-helsinki-finland","status":"publish","type":"post","link":"https:\/\/notesbard.com\/09-postdoctoral-jobs-at-university-of-helsinki-finland\/","title":{"rendered":"09 Postdoctoral Jobs at University of Helsinki, Finland"},"content":{"rendered":"

If you’re a PhD degree holder and seeking postdoctoral fellowships, University of Helsinki, Finland has several online applications open. Explore the opportunities across diverse research areas and submit your application soon.<\/span><\/p>\n

1. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

The research in this project is focused on structural biology and biophysics of protein interactions in neuronal synapse function and in regulation of synapse loss in Alzheimer\u2019s disease (AD) by the complement system (see e.g Chernyaeva et al. EMBO Reports (2023)). We have long standing interest in complement research (e.g. Kajander et al. PNAS (2011); Bhattacharjee et al. J Biol Chem (2013)), and synaptic adhesion (e.g. Karki et al. Sci Reports (2020), Kim et al. PNAS (2022)). Other projects in the group focus currently e.g. on endoplasmic reticulum stress response regulation, and overall on the HiLIFE protein crystallization core facility operation and related projects.<\/span><\/p>\n

Application Deadline:<\/strong> 30.06.2024<\/span><\/p>\n

View Details<\/span><\/strong><\/span><\/a><\/p>\n

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2. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

Spatial tumor-immune interactions are key determinants of therapy responses in ovarian cancer. Our aim is to identify the spatial transcriptional regulation of tumor cell states that drive chemoresistance in ovarian cancer. In this project, we will integrate multiplexed single-cell spatial proteomics, transcriptomics and chromatin states using unique novel spatial technologies and analytical methods. The two EMBL groups have highly synergistic approaches enabling an unprecedented analysis and exploitation of rich spatial multi-omics datasets generated in a unique prospective clinical trial (NCT06117384). The results will pave the way for the development of more effective treatments for ovarian cancer patients.<\/span><\/p>\n

Application Deadline:<\/strong> 31.5.2024<\/span><\/p>\n

View Details<\/span><\/strong><\/span><\/a><\/p>\n

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3. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

Human tumors are characterized by recurrent mutations in the well-defined cancer driver genes, but also non-mutational epigenetic reprogramming and phenotypic plasticity controlled by transcription factors (TF) are important contributors to tumorigenesis. Extensive consortium efforts have mapped the mutational and epigenetic landscapes of human cancers. However, the commonly used epigenomics methods such as ChIP-seq are correlative in nature and report a lot of spurious sites that might not be linked to gene expression, highlighting the need for novel innovative approaches to understand cancer genome and epigenome. Here, we will utilize cutting-edge long-read nanopore sequencing combined with deep machine learning approaches to model the epigenetic changes and mutational mechanisms in cancers originating from endodermal tissues. The goal is to reveal novel mechanistic details about the development of human cancer.<\/span><\/p>\n

Application Deadline:<\/strong> 31.5.2024<\/span><\/p>\n

View Details<\/span><\/strong><\/span><\/a><\/p>\n

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4. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

The university researcher is expected to develop and apply inverse methods to integrate multidisciplinary data. The University of Helsinki maintains an extensive network of permanent seismic stations, biological field stations, and atmospheric stations, making multidisciplinary data sets available for new research avenues. A key element in the research is the joint analysis of continuous or campaign seismic, solid earth geophysical, geoscientific, and environmental data collected by a variety of modern sensor and data acquisition systems. These include the domestic infrastructures of the Finnish national seismic network and instruments of the, as well as geoscientific and environmental data from research field stations, infrastructures including ACTRIS, ICOS, LTER, AnaEE and the EPOS data portal, for example.<\/span><\/p>\n

Application Deadline:<\/strong> 31.5.2024<\/span><\/p>\n

View Details<\/span><\/strong><\/span><\/a><\/p>\n

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5. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

Pyramidal neurons in the mammalian cortex use complex dendrites to integrate input from diverse brain regions in a parallel manner. To enable parallel processing, local intracellular organelles involved in synaptic metabolism such as the endoplasmic reticulum (ER) and mitochondria are fine-tuned to local synaptic function. So far, we do not have a complete landscape of ER and mitochondria distribution in individual neurons. This project will 1) mine existing electron microscopy (EM) connectomics databases to reconstruct the ER and mitochondria landscape for individual cortical pyramidal neurons and investigate this organelle landscape in relation to known electrophysiological features of individual neurons.<\/span><\/p>\n

Application Deadline:<\/strong> 31.5.2024<\/span><\/p>\n

View Details<\/span><\/strong><\/span><\/a><\/p>\n

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6. Postdoctoral Job<\/span><\/h1>\n

Summary of Postdoctoral Fellowship:<\/span><\/strong><\/span><\/h2>\n

The FAME project aims to transfer insights and algorithms from the mathematics of inverse problems to a diverse range of societally relevant applications. The research scope of our FAME team includes the following themes:
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