{"id":11824,"date":"2024-06-16T23:00:13","date_gmt":"2024-06-16T23:00:13","guid":{"rendered":"https:\/\/notesbard.com\/?p=11824"},"modified":"2024-06-09T00:38:20","modified_gmt":"2024-06-09T00:38:20","slug":"12-postdoctoral-jobs-at-institut-pasteur-paris-france","status":"publish","type":"post","link":"https:\/\/notesbard.com\/12-postdoctoral-jobs-at-institut-pasteur-paris-france\/","title":{"rendered":"12 Postdoctoral Jobs at Institut Pasteur, Paris, France"},"content":{"rendered":"
If you’re a PhD degree holder and seeking postdoctoral fellowships, Institut Pasteur, Paris, France has several online applications open. Explore the opportunities across diverse research areas and submit your application soon.<\/span><\/p>\n A postdoctoral position is available to study dynamic processes in early development of insects and mammals. Successful candidates will join a collaborative and interdisciplinary venture in the newly formed unit Physics of Biological Function of biophysicist Thomas Gregor.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n Our laboratory is part of the Neuroscience Department of the Institut Pasteur and gathers psychiatrists, neuroscientists and geneticists to understand the causes of autism. We previously identified the first mutations in the NLGN-NRXN-SHANK pathway, which has a key role in synapse formation within the brain. Our results highlight the genetic heterogeneity of autism, but also point at common biological mechanisms that could constitute relevant targets for new treatments. We are leading the genetic work package of AIMS-2-TRIALS, the largest European project on autism research.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n Humoral immunity is essential to host protection against human infections, and relies on the phenomenal diversity of antibody molecules sensing and inactivating pathogens. Our understanding of pathogen-specific B-cell responses has increased substantially in recent years with the advent of modern technologies permitting the fine characterization of single B-cell-derived human monoclonal antibodies. Our lab studies at a serological, cellular and molecular level, principally by generating and characterizing virus-specific antibodies, the human humoral responses to viruses i.e., HIV-1, Hepatitis E and B, as well as emerging viruses such as SARS-CoV-2.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n Our laboratory is part of the Neuroscience Department of the Institut Pasteur and gathers psychiatrists, neuroscientists and geneticists to understand the causes of autism. We previously identified the first mutations in the NLGN-NRXN-SHANK pathway, which has a key role in synapse formation within the brain. Our results highlight the genetic heterogeneity of autism, but also point at common biological mechanisms that could constitute relevant targets for new treatments. We are leading the genetic work package of AIMS-2-TRIALS, the largest European project on autism research. The project is focused on deep-phenotyping of individuals with autism and controls including brain imaging (MRI, fMRI, DTI and EEG) and a battery of cognitive tests.\u00a0<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n We are looking for a computational biologist\/bioinformatician at the postdoc\/research assistant level to join the ERC Synergy project DecoLeishRN (https:\/\/cordis.europa.eu\/project\/id\/101071613). The candidate will apply and develop computational tools for the analysis of large data sets generated by short-read, long-read, and single cell DNAseq\/RNAseq analyses of cells evolving in vitro in culture and in vivo in infected animals. The major aim of his\/her project is to understand how Leishmania can harness its intrinsic genome instability for the evolution of beneficial phenotypes.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n Type IV pili machineries are bacterial molecular nanomachines found in numerous pathogenic bacteria that allow the dynamic assembly of a polymeric fiber composed of one protein, the major pilin. These fibers play essential roles in bacterial physiology and pathogenesis. Recent approaches allowing the visualization of type IV in real time revealed that these filamentous structures form by the assembly of a staggering 1000 monomers per second and can disassemble at the same speed. A physical understanding of these extremely fast processes, which combine passive diffusion of monomers and their active, motor driven assembly\/dissaembly, is still missing.\u00a0<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n Our group is interested by the fine tuning of cell death in epithelial context using Drosophila as a model system (https:\/\/research.pasteur.fr\/en\/team\/cell-death-and-epithelial-homeostasis\/). We use a wide range of live imaging technics, live sensors, optogenetic, image analysis (including machine learning assisted cellular event recognition) and modeling to dissect quantitatively the feedback fine tuning cell death. Our pojects are currently focusing on studying the impact of mechanical stress on apoptosis regulation, the role of apoptosis in the fine tuning of tissue growth and morphogenesis, the coupling between proliferation and death, the coordination of cell extrusion by caspases and the fine tuning of epithelial cell death decision downstream of caspase activation.\u00a0<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n Leptospirosis is a re-emerging neglected zoonosis as climate and demographic changes fuel ideal conditions, including rising inequality, for rat-borne transmission to humans. Despite these concerning projections, little is known about the ability of the etiologic agent to adapt to different hosts and cause disease. Leptospira remains a challenging genus on which to perform genetic studies and is characterized by a high proportion of proteins of unknown function not present in other pathogens. This is generally also true for other spirochetes which are an ancestral and unique group of bacteria including the agents of important infectious diseases including Lyme disease and syphilis.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n The objective of the postdoc work is to draw inspiration from the neuronal structures of insects to produce classical neural networks (DNN) and spiking neural networks (SNN) which are both highly compressed and frugal in energy as well as ‘in training data. One of the main obstacles to be overcome is the formalization of a methodology allowing the transfer of knowledge and biological results to the creation of DNN and SNN neural networks. You will carry out this formalization work in close collaboration with the teams at the Institut Pasteur. You will then apply this methodology to the design and implementation of bio-inspired DNN and SNN neural networks and demonstrate the relevance of the approach through in-depth tests of their performance (computational and energetic).\u00a0<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n We are looking for a computational biologist interested in pathogen evolution to join us to work on exciting projects combining molecular epidemiology and functional studies of arboviral infections. The aim of the current project is to study dynamics of arbovirus emergence or endemic circulation, and the underlying mechanisms, at the scale of individual outbreaks through the integrated analysis of genomic, temporal and functional data.<\/span><\/p>\n Application Deadline:<\/strong> Open Until Filled<\/span><\/p>\n View Details<\/span><\/strong><\/span><\/a><\/p>\n <\/p>\n We seek a post-doc or bioinformatician with experience in microbial population genomics to develop and benchmark novel strain subtyping schemes and nomenclature systems for genomic subtyping of bacterial pathogens. We offer a 1-year contract (possibly extensible); the position is available from July 2024. The selected candidate will work in the group of Sylvain Brisse and at the Biological Resources Center of Institut Pasteur (CRBIP), within the BIGSdb-Pasteur project team and with external collaborators of the project CENTAUR \u2013 \u201cCreating and refining whole-genome and core-genome typing schemes for pathogen surveillance\u201d, coordinated by Mario Ramirez (University of Lisbon, Portugal.<\/span><\/p>\n1. Postdoctoral Job<\/span><\/h1>\n
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\nThe successful candidate will join and collaborate with a vibrant, international team that applies experimental evolution to study mechanisms of fitness gain in the eukaryotic pathogen Leishmania.
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