If you’re a Masters degree holder and seeking Fully Funded PhD Programs, University of Plymouth, England has several online applications open for PhD programs. Explore the PhD opportunities across diverse research areas and submit your application soon.
1. Fully Funded PhD Position in Determining the dietary accumulation and toxicity of nanoplastics and nanomaterials in fish
Summary of PhD Program:
Plastic pollution represents a global environmental challenge. Larger pieces of plastic can degrade to produce and release nanoplastics (NPs; <1 micron) that can enter the tissues of animals. In fish, NPs can pass across the gut epithelium in a matter of hours and then distribute around the rest of the internal organs.
Pollution such as NPs do not occur alone in the environment, but rather in the presence of other pollutants (or co-contaminants). These other pollutants may have effects on how the NPs enter animals, and the subsequent effects they may have. Other common pollutants include engineered nanomaterial (such as zinc oxide), as their manufacturing is increasing due to their use in electronic devices. However, the effect of combined NP and ENM exposure on animal physiology remains poorly understood.
Application Deadline: 17 July 2024
2. Fully Funded PhD Position in Comparing toxicological response in fish and human cells in vitro
Summary of PhD Program:
Both animal and human cells express toxicological responses through highly conserved biological pathways when under stress. Elucidating common cellular response pathways in phylogenetically different cell types employing in vitro approaches is needed with an overall goal to harmonise the hazard and risk assessments. This inevitably requires adoption of New Approach Methodologies (NAM). Precise comparison of cascades of responses in established cell lines of different origins are however scarce. Whilst for human cells a range of ‘biomarker’ responses is employed to elucidate both non-specific and specific toxicity of chemicals, there has been limited progress for cells of fish origin. The necessity to adopt a common approach is being emphasized, despite inherent differences in these cell lines.
Application Deadline: 4 July 2024
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3. Fully Funded PhD Position in Improved physical modelling techniques for new high capacity floating offshore wind turbines
Summary of PhD Program:
This PhD will explore the use of two techniques for overcoming this challenge, to enable the testing of high capacity FOWT. The first technique involves the wind turbine being replaced with thrusters which apply correctly scaled aerodynamic loads to the floating platform. The generated loads are controlled in real time using a surrogate model ‘trained’ using results from more complex numerical models. In the second approach COAST’s new 3 m x 2.8 m wind generator will be used to generate a wind field over the Ocean Basin. A model turbine will be installed on the scaled floating platform to generate the aerodynamic loads.
Application Deadline: 5 July 2024
4. Fully Funded PhD Position in Recreating brain tumours using patient-derived glioma stem cells hosted by normal brain cells to gain novel insights into tumourigenesis
Summary of PhD Program:
Glioblastoma remains as an incurable brain tumour, with a median survival of 15 months. Major reasons for treatment failure include tumour heterogeneity, extensive infiltrative behaviour and the glioma stem cells (GSC), a subpopupation of tumours able to reform all tumour masses. These clinically relevant properties are not always recapitulated with traditional in vitro models, likely contributing to low success of clinical trials and highlighting the need for more translatable systems. Cerebral organoids, or mini-brains, are one of the most promising advances providing a physiological 3D substrate for glioma stem cells (GSC) to generate tumours that more closely mirror patient ́s GBMs. This PhD project aims to develop models towards human neural spheroids and/or organoids, and use these “mini-brain” platforms to generate infiltrative tumours using patient-derived GSCs. The model will then be validated as a more clinically relevant system to reveal novel mechanisms of tumour development and therapeutic resistance.
Application Deadline: 12 August 2024
5. Fully Funded PhD Position in Psychology
Summary of PhD Program:
Research in the School covers a wide range of topics in areas such as cognition, learning, memory, developmental, emotion, health, clinical, decision making, social psychology, and neuroscience. It is essential that candidates discuss their proposal/plans with their intended supervisor(s), prior to writing their proposal and submitting an application. The School can only consider proposals in areas in which we have expertise to supervise a topic.
Application Deadline: 21 June 2024
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6. Fully Funded PhD Position in Choroid Plexus Pathology in Multiple Sclerosis and Alzheimer’s Disease
Summary of PhD Program:
Disability and dementia define the devastating diseases Multiple Sclerosis (MS) and Alzheimer’s Disease (AD), but what drives the neuroinflammation and neurodegeneration? New research is focusing on the choroid plexus (ChP), a highly vascular structure hidden deep in the brain’s fluid-filled cavities. ChP is emerging as a major interface between the peripheral immune and central nervous system, an area of increasing importance in MS and AD. However, ChP also transports thyroid hormone (TH) into cerebrospinal fluid (CSF) which is then distributed throughout the brain.
Application Deadline: 30 June 2024
