Karolinska Institute has huge a campus in Sweden and widely known as for its contribution in top notch education and research. The contribution of Karolinska Institute is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc..

1. Postdoctoral studies in Cancer Genetics (scholarship) – for Ukranian researcher

Summary of Postdoctoral Fellowship:

We investigate genetic disorders on a molecular level in a translational research setting in order to understand disease mechanisms, apply new knowledge in genetic diagnostics, improve prognosis assessment and develop new treatment strategies. Our research group consists of four teams and our main interests are hematological malignancies, with a particular focus on chronic lymphocytic leukemia, lymphoma and pediatric acute lymphoblastic leukemia, metabolic bone disorders, and cancer genetics.

Last Application Date: 30.Sep.2022

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2. Postdoctoral Position in Computational Biology of Parkinson’s Disease at the single-cell level

Summary of Postdoctoral Fellowship:

We are looking for a creative computational biologist seeking to study neurodegeneration in Parkinson’s disease at the single cell level. The project involves analysis of single cell RNA-seq, multiome and in situ sequencing data generated from different brain regions of control and Parkinson’s disease patients. You will use your experience in performing bioinformatics analyses of sequencing data, to analyze and integrate transcriptomics and epigenomics data. You will have your own project, and you will be encouraged to address challenging questions, think independently and develop high impact research. You will interact and collaborate with other lab members working in the dry and the wet lab. The successful candidate will also have the opportunity to supervise students and to achieve personal development.

Last Application Date: 02.Sep.2022

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3. Postdoctoral researchers in Cell transplantation for Parkinson’s disease

Summary of Postdoctoral Fellowship:

We look for postdoctoral researchers interested in stem cell biology and in developing cell replacement strategies for Parkinson’s disease. The successful candidate will transplant neural progenitors derived from pluripotent stem cells in transgenic mouse models of Parkinson’s disease (PD) or in 6-hydroxydopamine models of PD. Applicants will work on one of the two following projects: 1) Identification of the optimal cell preparation and cell composition to achieve precise and effective cell replacement with the minimal number of cells and cell types. Focus will be placed on appropriate integration of cells in the host brain at an anatomical level (establishment of afferent and efferent projections); at a functional level (electrophysiological, neurochemical and behavioral analysis); and at a molecular level, by using as single cell methodologies.

Last Application Date: 02.Sep.2022

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4. Applications are invited for a postdoctoral position in Onur Dagliyan’s Group

Summary of Postdoctoral Fellowship:

Neuronal activity dependent molecular signaling processes are central for brain development and plasticity. These molecular events form the mechanistic basis of complex neural computation, learning and memory. Experience-driven activation of proteins often at the post-translational level mediate the rapid events including synaptic modifications, metabolic adaptations, and the transfer of the cytosolic protein signals into the nucleus to influence gene expression. The Dagliyan laboratory focuses on specific molecular events in neurons happening at these different time scales, starting from the immediate modifications at the synapse, such as actin-modifying protein signaling, to longer time scale molecular events such as protein modifications that mediate transcription initiation, elongation, and RNA splicing, which are key processes for the behaviorally induced plasticity of neuronal circuits.

Last Application Date: 01.Sep.2022

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5. Postdoctoral Researcher in Materials Science

Summary of Postdoctoral Fellowship:

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry. Description of Research Group and Position The current research of Assistant Professor Sijie Chen aims at developing novel fluorescence-based tools and technology for biological research. One Postdoctoral Researcher position in Materials Science is available.

Last Application Date: 31.Aug.2022

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6. Postdoctoral Researcher in metabolomics of asthma

Summary of Postdoctoral Fellowship:

We have an opening for an individual wishing to join a multidisciplinary project aimed to develop quantitative methods for molecular phenotyping of asthma. Based upon our previous metabolomics studies on asthma, the aim of this project is to develop targeted quantitative methods for personalized medicine applications in asthma. The successful candidate will be expected to use and further develop mass spectrometry-based methods for quantification of small polar compounds and lipids. The methodology will be formatted for high-throughput application in 96-well plate format using automated sample preparation techniques. Developed methods will be employed in multiple large-scale clinical studies, with a focus on interventional studies and precision pharmacotherapy with novel biologics (e.g., mepolizumab, omalizumab). This project will be performed in collaboration with researchers at the Harvard Medical School.

Last Application Date: 31.Aug.2022

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7. Postdoctoral Researcher in lipid bioanalytical chemistry of respiratory disease

Summary of Postdoctoral Fellowship:

We have an opening for an individual wishing to join a multidisciplinary project aimed to understand the role of lipid mediators in lung disease. The successful candidate will be expected to use and further develop mass spectrometry-based methods for quantification of lipid mediators including eicosanoids (e.g., prostaglandins, leukotrienes), novel octadecanoids and structural lipids. Analyses will involve further development of novel chromatography approaches including chiral and UPC2 methods for applications in large scale clinical studies as well as experimental models to map the biochemical role of lipid mediators in the pathobiology of lung disease. Functional studies will be performed in multiple cell types, in ex vivo lung tissue as well as in animal models to generate a biochemical map of both pro-inflammatory and pro-resolving lipid mediators. This project will be performed in collaboration with researchers at the University of California San Francisco (UCSF).

Last Application Date: 31.Aug.2022

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8. Postdoctoral position in the area of single-cell genomics

Summary of Postdoctoral Fellowship:

Ana Mendanha Falcão is a research group leader focusing on the role of the choroid plexus in diseases such as multiple sclerosis. Her team aims to investigate the choroid plexus as a source of biologically active molecules to the central nervous system, in order to influence disease dynamics. The choroid plexus is studied as an alternative target for disease therapies since it can be modulated by peripheral blood and it can substantially alter the brain composition both in terms of biologically active molecules and immune cell content. The Castelo-Branco research group is interested in the molecular mechanisms defining the epigenetic state of cells of the oligodendrocyte lineage. Our research group has performed single nuclei/cell RNA-Seq and ATAC-seq and identified several cell states within the oligodendrocyte lineage in development and disease (Nature Medicine 2018, Nature 2019, Neuron 2022), including an immune state that might be relevant for the etiology and/or progression of MS.

Last Application Date: 31.Aug.2022

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9. Two Postdoctoral Researcher/ The Strategic Research Programme for Diabetes

Summary of Postdoctoral Fellowship:

We are interested in understanding how skeletal muscle insulin sensitivity is altered, both in response to pathology such as type diabetes, and as a response to physical exercise. This fellowship programme is focused on the role of miRNAs in this regard, in particular miRNAs in small extracellular vesicles (also called exosomes. We have previously identified several miRNA which are dysregulated in skeletal muscle in subjects with type 2 diabetes, and which contribute to changes in metabolism and insulin signalling, including let7 (Jiang et al., 2013), miR-29 (Massart et al., 2017) and mIR20b (Katayama et al., 2018). Since miRNAs are able to target multiple genes simultaneously, miRNAs provide a potential mechanism for efficiently modulating a whole pathway to change or alter the functional properties in specific target tissues.

Last Application Date: 31.Aug.2022

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10. Postdoctoral researcher in “Single cell multiomics of Parkinson’s disease”

Summary of Postdoctoral Fellowship:

We look for a postdoctoral fellow interested in working on a project aiming at understanding the molecular mechanisms behind neurodegeneration and the formation of neuromelanin and a-synuclein aggregates in Parkinson’s disease (PD). The project involves the use of human postmortem samples from PD patients as well as transgenic mouse models of PD. The goal of the project is to identify the molecular phenotypes of cell types from different brain regions by defining changes in gene expression, gene regulation and transcriptional networks at the single cell level, using a multiomics approach, in situ transcriptomics methods and computational tools. This project is supported by a Collaborative Research Network (CRN) program of the Aligning Science Across Parkinson’s (ASAP), an initiative implemented through The Michael J. Fox Foundation, which aims at understanding the cause and molecular mechanisms underlying PD.

Last Application Date: 15.Aug.2022

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11. Postdoctoral Researcher in Rare Skeletal Diseases

Summary of Postdoctoral Fellowship:

We are interested in candidates with prior experience on a variety of genetic methods, e.g., exome and whole-genome sequencing data analysis, Sanger sequencing, and transcriptome analysis as well as familiarity with high performance computing environment, Linux, phyton, R scripting or other programming language. Other advantageous skills may include data analysis of short- and long-read sequencing (e.g., Oxford Nanopore, PacBio) as well as optical mapping (e.g., Bionano), and experience with whole genome methylation analysis. Once a disease-causing gene variant is found, the researcher will work together with other experts in the team to establish in vitro cell models to validate the findings.

Last Application Date: 15.Aug.2022

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12. ONE Postdoctoral Researcher in chemical and genetic screens

Summary of Postdoctoral Fellowship:

We are looking for a postdoctoral scientist to join our team with a Ph.D. in Cell Biology, Molecular Biology, Biochemistry or other relevant fields. A background in senescence, cell cycle or DNA damage signaling would be a merit. We are specifically looking for a highly motivated scientist, who aims to complement his/her skills with experience in large chemical and genetic screens and has the capacity to independently develop a scientific research project that relies mostly on cell and molecular biology technologies. In addition, it is expected that the candidate will help in the training of junior group members. Other valuable skills such as writing or presenting capacities or social skills will also be appreciated.

Last Application Date: 02.Aug.2022

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13. Postdoctoral researcher in Developmental/ Computational Neurobiology (scholarship)

Summary of Postdoctoral Fellowship:

The Marklund lab addresses principal questions in ENS biology with a focus on neural cell diversity. The team has recently identified molecularly distinct neuronal cell classes in the ENS as well as a new conceptual model for they emerge during the development (Morarach et al., 2021). These discoveries form the basis for an ERC-funded project, requiring an expansion of the team. The new project seeks to uncover molecular programs controlling cell fate decisions during embryonic and adult enteric neurogenesis and thereafter apply these insights to engineer specific neuron types within the adult gut wall. A wide range of transcriptomic, epigenetic, cellular, and imaging methodologies will be utilized to meet these aims. By resolving mechanisms of ENS development, the lab hopes to pave the way for a better understanding, characterization and treatment of prevalent gut disorders.

Last Application Date: 01.Aug.2022

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14. Postdoctoral Researcher in Enteric Neurobiology (scholarship)

Summary of Postdoctoral Fellowship:

The Marklund lab addresses principal questions in ENS biology with a focus on neural cell diversity. The team has recently identified molecularly distinct neuronal cell classes in the ENS as well as a new conceptual model for they emerge during the development (Morarach et al., 2021). These discoveries form the basis for an ERC-funded project, requiring an expansion of the team. The new project seeks to uncover molecular programs controlling cell fate decisions during embryonic and adult enteric neurogenesis and thereafter apply these insights to engineer specific neuron types within the adult gut wall. A wide range of transcriptomic, epigenetic, cellular, and imaging methodologies will be utilized to meet these aims. By resolving mechanisms of ENS development, the lab hopes to pave the way for a better understanding, characterization and treatment of prevalent gut disorders.

Last Application Date: 01.Aug.2022

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15. Postdoctoral researcher of mRNA translation in cancer

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. Although the focus for this project will be to use advanced molecular biology approaches to study mRNA translation in cancer, there will also be opportunities to learn analysis of large-scale data sets.

Last Application Date: 01.Aug.2022

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16. Postdoctoral Researcher in Computational Biology

Summary of Postdoctoral Fellowship:

We are recruiting a highly motivated and independent postdoc candidate with experience in next-generation sequencing data analysis, computational genomics, medical statistics, computational biology and/or imaging analysis. The project combines single-cell, multi-omics data with large scale human genetics to investigate the cellular origin of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). The postdoc candidate will work closely with researchers in the team as well as with our collaborators and be responsible for data analysis, visualization, and development of new computational methods for processing and analysis of large-scale omics data. We welcome applications from candidates with pure computational background and those combining experimental and theoretical approaches.

Last Application Date: 31.Jul.2022

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17. Postdoctoral researcher in personalized medicine of infectious diseases

Summary of Postdoctoral Fellowship:

The ideal candidate should hold a Doctoral (or be near completion) degree in medicine, epidemiology, statistics, biostatistics, mathematics, computer science, health data sciences or a related field. An advantage is having worked with large amounts of clinical data or registers, and knowledge of programs such as R, STATA, SAS or Python. You should have experience of independent work, good communication and teamwork skills. A requirement is good knowledge of English, knowledge of Swedish is beneficial. Knowledge of statistics, machine learning techniques, database management, an understanding of clinical work, or infectious diseases is an advantage.

Last Application Date: 31.Jul.2022

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18. Postdoctoral Researcher in Bioinfomatics

Summary of Postdoctoral Fellowship:

The WHO research group in the department of Women’s and Children’s health is headed by Professor Kristina Gemzell Danielsson. The group’s work on translational medicine in the field of women’s reproductive health covers a wide spectrum of clinical, experimental and global reproductive health. One of the research field the group has worked extensively is the development and clinical application of progesterone receptor modulator in its clinical application. The team on experimental research in the laboratory is led by Associate Professor Lalit Kumar and has a focus on infertility, endometrial function, embryo implantation, endometriosis and prevention of breast cancer.

Last Application Date: 31.Jul.2022

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19. Postdoctor in Immunology

Summary of Postdoctoral Fellowship:

The project aims to study basic scientific questions regarding the regulation and function of B cell responses to relevant viral antigens, with the goal to gain insights in how to design future vaccines that induce optimal protection against specific viral infections. The team has established genetically modified mouse models and immunogens that will be used to evaluate these questions. In addition to taking the lead and advancing the specific research project(s), it is expected that the candidate contributes to common laboratory duties and participates in the supervision of research students.

Last Application Date: 31.Jul.2022

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20. Postdoctoral Researcher in Molecular and Cell Biology

Summary of Postdoctoral Fellowship:

Dr. Linxian Li’s group has long interest in developing novel therapeutics for clinical applications. Committed to translating new technology for medical use, the Li group focuses on using chemical synthesis, biological tools, and artificial intelligence to develop mRNA therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in Molecular and Cell Biology.

Last Application Date: 27.Jul.2022

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21. Postdoctoral Researcher in Computational Eicosanoid Research (scholarship)

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoctoral researcher in structural bioinformatics. The candidate is expected to participate in collaborative efforts to simulate leukotriene pathway enzymes with coarse-grained and atomistic simulation methods, in order to generate and test predictions in the lab. Advanced knowledge in structural bioinformatics and proven experience with molecular simulation tools (GROMACS, CHARMM, etc), multiscale and coarse-grained approaches is a prerequisite. The applicant must be well acquainted with programming & scripting languages common in the biomolecular simulation field (bash, python, etc). Previous experience with simulations of membrane proteins, knowledge of complimentary structural analysis techniques (Network Analysis, PCA, etc) and additional molecular modelling methods (docking, virtual screening, etc) will be highly valued.

Last Application Date: 27.Jul.2022

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22. Postdoctoral Researcher in RNA Biology

Summary of Postdoctoral Fellowship:

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

Last Application Date: 27.Jul.2022

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23. Postdoctoral Researcher in Psychiatric Genetic Epidemiology

Summary of Postdoctoral Fellowship:

Dr. Bergen’s group conducts research investigating the genetic and environmental risk factors for psychiatric disorders, specifically, schizophrenia, bipolar disorder, eating disorders, and depression. Projects within this research area will be possible upon agreement, making use of the exceptional data from the Swedish National Registers and several genetically informed collections across a range of psychiatric disorders collected within Sweden. The open position is for a postdoctoral researcher for at least one year, and the position must start in September 2022 or earlier.

Last Application Date: 25.Jul.2022

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24. Postdoctoral studies in mitochondrial biology

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoctoral researcher interested in mitochondrial biology. Our research aims at identifying the molecular consequences of metabolic derangements, by understanding how mitochondria function within the metabolic system. For this, we use model systems, ranging from patient-derived samples, reprogrammed neuroepithelial stems cells to genetically modified animal models. We are specifically interested in the regulation of mitochondrial gene expression and post-transcriptional and post-translational modifications. The laboratory offers an outstanding research environment for basic and translational research with a close association to the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital.

Last Application Date: 20.Jul.2022

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25. Postdoctoral studies in Immunology to HERM / NEO (scholarship)

Summary of Postdoctoral Fellowship:

Professor Petter Höglund leads a translational immunology group with a focus on natural killer (NK) cells, platelets and neutrophils. See https://ki.se/en/medh/petter-hoglund-group for more information. The group is looking for a motivated, well-organized postdoctoral scientist to study the mechanisms underlying interactions between platelets and neutrophils with immune effector cells such as monocytes, macrophages and NK cells. There will be an initial focus on developing novel platforms for functional characterization of these interactions. The main responsibility will be to develop and conduct independent research projects at the postdoctoral level within the line of ongoing research in the group. The candidate is expected to provide expertise and constructive collaborative efforts into ongoing projects, including providing supervision of project students. Laboratory work in the group includes all aspects of an immunology lab, such as molecular biology, cell culture, flow cytometry, confocal and super-resolution imaging.

Last Application Date: 20.Jul.2022

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26. Postdoctoral position in viral immunology

Summary of Postdoctoral Fellowship:

The Buggert group conducts innovative studies of cell-mediated immunity in health, cancer, and viral disease. These studies are translational and involve the usage of cutting-edge bulk- and single-cell technologies, including high-parameter flow cytometry, gene-editing, RNA-seq, ATAC-seq, TCR-seq, and proteomics analysis to dissect the heterogeneity and function of memory T cell immunity. Through these platforms, we study different aspects of human memory T cell biology, with an overall aim to i) study the heterogeneity of circulating and resident memory T cells in human organ donors, ii) identify alternative functions of memory T cells in human tissues, and iii) understand how memory T cells maintain control of tumors and viral infections, such as SARS-CoV-2.

Last Application Date: 19.Jul.2022

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27. 1-4 postdoctoral scholarships in pharmacoepidemiology and causal inference

Summary of Postdoctoral Fellowship:

We seek dedicated and creative postdoctoral researchers to join our team. You will be involved in studies exploring the conditions of use (adherence, compliance, off and on-label use) and the effect (effectiveness, safety) of a number of licensed drugs and devices in ‘real world’ (routine practice) conditions. You will study unique data sources, including several Swedish Quality Registers and the Stockholm CREAtinine Measurements (SCREAM) project, a longitudinal administrative healthcare utilization cohort of >3 million residents of Stockholm with complete information on undertaken laboratory measurements. We employ both classic and advanced statistical methods, within the target trial emulation framework and with particular emphasis on causal inference statistics.

Last Application Date: 15.Aug.2022

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28. Postdoctoral researchers in “Astrocyte-to-neuron conversion for cell replacement in Parkinson’s disease”

Summary of Postdoctoral Fellowship:

We look for two postdoctoral fellows interested in developing precision cell replacement strategies for Parkinson’s disease based on cell engineering. Our laboratory has previously provided proof of concept that the conversion of astrocytes into midbrain dopamine neurons in vivo can rescue motor deficits in a mouse model of PD (Rivetti di val Cervo, 2017, Nature Biotechnology). We now aim at further developing these technologies, at improving the functionality of the converted DA neurons and at understanding the reprogramming process in grater detail by using, amongst others, single cell RNA-sequencing methodologies and computational tools to ascertain the quality of the DA neurons (La Manno et al., 2016, Cell; Nishimura et al., 2022, in preparation). Different aspects of the process of converting disease-associated astrocytes into induced midbrain dopaminergic neurons of the substantia nigra subtype, will be examined.

Last Application Date: 15.Aug.2022

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29. Postdoctoral Researcher in experimental psychology

Summary of Postdoctoral Fellowship:

You will be working at the National Centre for Suicide Research and Prevention (NASP) as part of an international team that is focused on research in the field of mental health and suicide prevention. As a postdoc you will design the protocols of the studies required by these projects, supervise their implementation, analyse quantitative data and lead the preparation of manuscripts reporting the findings. You will also offer scientific support and collaborate in work related to these projects such as participation and presentations in the technical project meetings, writing reports on the progress of the ongoing projects to the research Consortium, as well as assisting in project and financial management.

Last Application Date: 14.Aug.2022

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30. Postdoc in epidemiology using ensemble methods and big data

Summary of Postdoctoral Fellowship:

Common mental disorders (CMD) are the leading causes of long-term sickness absence. You will explore the relation between shift work (especially night work), long working hours and CMDs, as well as the interaction with psychosocial work environment. The goal is to show that routinely collected data can be used to a) identify risk factors for CMD, b) identify workplaces with high risk of sickness absence and c) give the employer recommendations on how to design healthy schedules. We have established a cohort of over 60,000 individuals employed by Stockholm Region between 2008 and 2021. Detailed information on working hours is retrieved from registry-based payroll data for each working day during the study. You will use longitudinal multivariate analysis to investigate working hours in relation to CMD and sickness absence, also including interaction between working hours and psychosocial work environment. In a non-randomized pseudo trial design, we will study the effect of changing work schedules on CMD. Finally, we will use ensemble methods to identify models that can predict workplace risk of long-term sickness absence among employees. The employment is temporary for two years.

Last Application Date: 14.Aug.2022

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31. Postdoctoral Researcher in protein biochemistry and biotechnology

Summary of Postdoctoral Fellowship:

We work on making artificial spider silk and base our work on biotechnology and protein biochemistry. Our lab has invented the first method for producing artificial spider silk fibers and our current main research focus lies in improving the mechanical properties of these by protein engineering and development of the spinning device. The group is well funded by e.g. an ERC consolidator grant. By using next generation sequencing technologies we have increased our understanding of the silk production machinery and will use this knowledge to improve the artificial spider silk fibers further. We have published several articles in high ranked journals (Arndt et al. Adv Funct Mater. 2022; Rising & Johansson ACS Nano. 2021; Schmuck et al. Materials Today. 2021; Andersson et al. Nat Chem Biol. 2017; Kronqvist et al. Nat Commun. 2017; Rising&Johansson. Nat Chem Biol. 2015). The group consists of three PhD students, two technicians, four post docs and one researcher. We are located at Karolinska Institutet, campus Flemingsberg, and at SLU in Uppsala.

Last Application Date: 14.Aug.2022

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32. Up to two Postdoctoral Researchers in experimental psychology with a focus on the behavioral defense against disease

Summary of Postdoctoral Fellowship:

We are currently looking for up to two postdoctoral researchers who will be working on several research projects in a research group lead by Professor Mats J. Olsson in close collaboration with Research specialist Arnaud Tognetti with a focus on the behavioral defense against disease. Behavior is arguably a cost-effective and first-line defense against disease. Using primarily experimental design (IRL and web-based), we investigate the physiological (including fMRI and immune response markers), perceptual, motivational and emotional processes that promote adaptive behavior in relation to sick kin and strangers.

Last Application Date: 07.Aug.2022

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33. ERC fundend postdoctoral scholarship: Exploring drivers of intratumor heterogeneity and phenotypic plasticity

Summary of Postdoctoral Fellowship:

We are seeking a motivated, creative post-doctoral candidate interested in exploring drivers of intratumor heterogeneity and phenotypic plasticity in sympathoadrenal tumors, such as childhood neuroblastoma and pheochromocytoma. Intratumor heterogeneity and high plasticity account for therapy resistance. Causes of plasticity cell state transitions during tumor progression remain poorly understood. Currently, there is no effective treatment that addresses cancer heterogeneity. Systematic characterization of dynamic properties of intratumor heterogeneity and phenotypic plasticity can guide treatment strategies and improve clinical outcome for cancer patients. We aim at elucidating the origin and heterogeneity of sympathoadrenal malignancies, such as pheochromocytoma and childhood neuroblastoma by developing a new analytic and experimental approach based on single-cell transcriptomics with integrated mass spectrometry. We generated novel tumor mouse model systems and include human tumors to perform comparative differentiation trajectory analysis, to make predictions and, finally, to perform preliminary validations of envisioned tumor differentiation strategies.

Last Application Date: 07.Aug.2022

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Karolinska Institute has huge a campus in Sweden and widely known as for its contribution in top notch education and research. The contribution of Karolinska Institute, Sweden is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc..

1. Postdoctoral studies in skin cell biology (scholarship)

Summary of Postdoctoral Fellowship:

The position is open for two highly motivated scientists with a strong background in experimental life science and proven expertise in cell and molecular biology. The applicants will be responsible for planning and performing various laboratory experiments relevant for the project as well as teaching other lab members. The research project is focused on the role of endoplasmic reticulum and mitochondria in skin biology, however the project may take different directions depending on the results. We are looking for two highly creative motivated persons with strong competence in running projects independently but that also having good abilities for team work and cooperation. Dermatology is a growing field with many job opportunities both inside and outside academia.

Last Application Date: 01.Jul.2022

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2. Postdoctoral Researcher to target mechanisms driving cancer cell growth

Summary of Postdoctoral Fellowship:

A postdoctoral position within the exciting field of gene regulatory networks in cancer is immediately available in the laboratory of Professor Jussi Taipale who heads research groups at Karolinska Institutet, University of Cambridge and University of Helsinki. This position is based at the Department of Medical Biochemistry and Biophysics, Karolinska Institutet. The laboratory focuses on the study of transcriptional control of cell growth, using functional genomics and systems biology and as such the research groups consist of both experimental biologists and computer scientists. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, using this information to identify regulatory elements that control cell growth during normal development or in cancer and validation of identified elements using cultured cells and mouse genetic models.

Last Application Date: 20.Jun.2022

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3. Postdoctoral researcher in epidemiology or biostatistics

Summary of Postdoctoral Fellowship:

Reproductive epidemiology focus on factors during pregnancy and delivery influencing maternal and offspring health, both shortly after delivery and long-terms risks. The proposed work will include collaboration between epidemiologists, statisticians, and clinicians working within this field at the Clinical Epidemiology Division, but also international collaboration with Canada. Data sources include primarily cohorts from national registers but also data from Stockholm and Gotland counties. The work will include studies of environmental factors and maternal and offspring health after delivery and later in life.

Last Application Date: 18.Jun.2022

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4. Postdoctoral Researcher in Computational Cognitive Neuroscience

Summary of Postdoctoral Fellowship:

The project is focused on increased understanding of our working memory, an integral part of flexible cognition. In particular, the underlying mechanisms that lend humans their ability to generalize will be investigated in this interdisciplinary project. The postdoc will conduct multiple studies using network simulations (typically abstract, non-spiking networks like RNNs), to explore this is artificial systems. Part of the studies will be to compare the outcome to human and non-human neural data.

Last Application Date: 15.Jun.2022

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5. Postdoctoral Researcher in Cognitive Neuroscience

Summary of Postdoctoral Fellowship:

The project is focused on increased understanding of our working memory, an integral part of flexible cognition. To this end, human cognitive and neuroimaging studies will be combined with analysis of data recorded intracranially in animal models (spikes, LFPs). In particular, the underlying mechanisms that lend humans their ability to generalize will be investigated in this interdisciplinary project. The postdoc will conduct multiple studies, both using EEG and MEG in human subjects as well as comparing EEG/MEG data to LFP data in animals.

Last Application Date: 15.Jun.2022

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6. Postdoctoral studies in Neuroimaging and Machine Learning in Aging and Neurodegenerative Diseases

Summary of Postdoctoral Fellowship:

A postdoctoral position (scholarship) is open in the Brain Connectomics Lab led by Principal Researcher and Associate Professor Joana B. Pereira, which consists of 4 PhD students and 2 Postdocs working at Karolinska Institute and Gothenburg University in Sweden. Our research is focused on developing new brain connectivity measures derived from structural MRI, functional MRI and diffusion tensor imaging in Aging and patients with Alzheimer’s disease and Parkinson’s disease. Moreover, many of our recent projects are also apply different machine learning algorithms to brain imaging data, including MRI, amyloid PET and tau PET in addition to cerebrospinal fluid and plasma biomarkers as well as clinical data to predict the development of cognitive decline and dementia.

Last Application Date: 10.Jun.2022

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7. Postdoctoral fellow for projects on mental illness in working life

Summary of Postdoctoral Fellowship:

The position as postdoctoral fellow is placed in a research group that conducts intervention studies in secondary prevention and rehabilitation in mental illness to facilitate return to work. The tasks involve conducting studies independently and in collaboration with project managers and the research group, primarily with a focus on data analysis and reporting of results. This includes, together with the research group, analyzing data and reporting results from randomized studies with different outcome measures linked to mental illness and sick leave. The projects study, for example, employees with mental illness and how the risk of sick leave can be prevented. In your role as a postdoctoral fellow, you will work with follow-ups of study participants via register data and survey data, perform data analyzes, and write scientific manuscripts.

Last Application Date: 2022-06-09

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8. Postdoctoral Researcher on Dementia Epidemiology

Summary of Postdoctoral Fellowship:

Within this network, Dr. Sindi conducts research on modifiable dementia risk factors such as stress and sleep disturbances, and the plan is to integrate studies on air pollution. The goal of this multi-site collaborative research plan is to investigate the mechanisms underlying the associations between the aforementioned risk factors and dementia/cognition, e.g. neuroimaging correlates (MRI, PET, MEG), Alzheimer’s disease biomarkers measures in cerebrospinal fluid (beta amyloid, tau), microbiome markers, and inflammatory markers. The specific postdoctoral project will be tailored to the postdoctoral fellow’s areas of expertise and research interests.

Last Application Date: 08.Jun.2022

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9. Postdoctoral researcher in Computational Biology

Summary of Postdoctoral Fellowship:

Postdoctoral Researcher in mucosal immunology with focus in single-cell RNA-seq and spatial transcriptomics analysis and data visualization. A postdoctoral position to study the transcriptomic landscape of intestinal tissue regeneration, with clear implications for intestinal diseases such as inflammatory bowel diseases (IBD) and colorectal cancer (CRC). The position is available in the laboratory of Dr. Eduardo Villablanca, who is a renowned leader in mucosal immunology (twitter @ejvillablanca). The candidate will be part of a research program that integrate experimental models, patient material and cutting-edge technologies (spatial and single cell transcriptomics) to understand how intestinal homeostasis is maintained and how breakdown in these processes might lead to IBD or CRC.

Last Application Date: 08.Jun.2022

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10. Postdoctoral Researcher in Mechanotransduction

Summary of Postdoctoral Fellowship:

We are looking for a Postdoc to Staffan Strömnblad´research group. The candidate will take an ongoing project to completion , regarding the role of mechanotransduction in cellular senescence. This includes handling transgenic mouse cancer models, tissue analysis, and in vitro cell models. You will work in a research group focusing on cell-matrix interactions and cellular signaling in cancer and will contribute to and benefit from an ambitious research environment.

Last Application Date: 08.Jun.2022

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11. Postdoctoral scholarship dedicated to the experimental analyses of molecular features driving the evolution of breast cancer

Summary of Postdoctoral Fellowship:

We are seeking an outstanding candidate for a post-doctoral fellowship dedicated to explore the synergisms between the epigenome and the 3-dimensional nuclear architecture to effectuate oncogene expression from new perspectives. The successful applicant is expected to drive a postdoctoral project in the labs of Anita Göndör at the department of Oncology and Pathology, as well as to participate in collaborative efforts with both national and international collaborative labs with a focus on breast cancer. Our lab is equipped with a Mi-seq machine and a 5-color confocal microscope, and is located within the Theme Cancer section of BioClinicum at Karolinska Institutet.

Last Application Date: 07.Jun.202

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12. Postdoctoral position (scholarship) in bioinformatics

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated postdoctoral researcher in bioinformatics to join a a research team dedicated to understand the function of 3D epigenome folding and its deregulation in human diseases from entirely novel perspectives. The candidate is expected to drive a postdoctoral project and participate in collaborative efforts to uncover hitherto unknown therapeutic targets in complex diseases, such as cancer. The work will be carried out at the department of Oncology and Pathology in the lab of Drs Anita Göndör. We have innovated state-of-the-art techniques enabling the analysis of 3D chromatin structures and chromatin fibre networks in single cells and small cell populations to provide unique opportunities for novel discoveries.

Last Application Date: 07.Jun.2022

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13. Postdoctoral fellow for projects in nursing

Summary of Postdoctoral Fellowship:

We are now looking for a postdoctoral fellow for a research project that aims to facilitate early diagnosis and treatment of lung cancer. The project has a translational nursing research approach and we combine patient-reported data about the perceived body (symptoms and ailments) and data about the biological body (biomarkers in the form of eg proteins and images). We have developed an instrument to investigate early health changes that can occur in lung cancer and in parallel with patient-reported data, we collect biological data for biomarker analysis. As a postdoctoral fellow, you will participate in leading and running the continuation of the project. The employment is 50-100% for one to two years with access by agreement. We are happy to see that access can take place as soon as possible.

Last Application Date: 2022-06-06

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14. Postdoctoral studies on beta-cell regeneration in zebrafish

Summary of Postdoctoral Fellowship:

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and metabolism. CMB is located in Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum houses approximately 1,200 researchers and other personnel and allow expensive equipment to be shared and used more effectively. The main interest in the lab of Olov Andersson is to study how small molecules can promote regeneration of insulin-producing beta-cells and improve metabolic control, as future curative approaches for diabetes. In an ERC-funded lab the successful applicant will use chemical-genetic screening techniques in zebrafish to identify compounds, genes and signalling pathways that can promote β-cell regeneration.

Last Application Date: 05.Jun.2022

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15. Postdoctoral Researcher in Materials Science

Summary of Postdoctoral Fellowship:

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

Last Application Date: 05.Jun.2022

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16. Postdoctoral studies on pathogenic mechanisms of the chronic complications of diabetes

Summary of Postdoctoral Fellowship:

The present project will span from molecular and cellular biology to translational studies using cellular and animal models as well as clinical samples. The candidate will use various methods to detect RNA and protein expression, such as QPCR, western blotting, flow cytometry, ELISA, immunohistochemistry and confocal microscopy. Cellular proliferation, migration, Seahorse metabolic flux assay, Electro Paramagnetic Resonance (EPR) measurements of ROS, plasmid or siRNA/miRNA transfection will also be performed.

Last Application Date: 05.Jun.2022

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17. Postdoctoral fellow in drug screening for beta cell regeneration in zebrafish

Summary of Postdoctoral Fellowship:

The main interest of the research group is to study how small molecules can stimulate regeneration of insulin-producing beta cells and improve glucose control, as future treatments for diabetes. In an ERC-funded laboratory, the applicant will use genetic and drug screening in zebrafish to identify and characterize chemicals, genes, and signaling pathways that may promote beta-cell regeneration.

Last Application Date: 2022-06-03

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18. Postdoctoral researcher in toxicology at the Unit of Integrative Toxicology

Summary of Postdoctoral Fellowship:

Your main task will be to work in the research project Novel in vitro approaches to quantify chemosensory irritation as basis for exposure limits, funded by the Swedish Research Council. You will plan and conduct experiments with zebrafish larvae including all parts, from handling of larvae, chemicals and video tracking instruments to analysis of data and compilation of manuscripts. Participation in general activities at IMM and the unit is expected. Participation in education including e.g. supervision of master students may be required.

Last Application Date: 03.Jun.2022

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19. Postdoctoral researcher in development of animal models in respiratory diseases

Summary of Postdoctoral Fellowship:

The main project is to design, plan, carry out and analyze results from physiological and pharmacological experiments on in vivo models for asthma and other lung diseases in mice and guinea pigs. These experiments involve the use of advanced technology for lung exposure and measurement of different parameters for lung function. Another part of the project is to perform laboratory analyses such as histological examinations, flow cytometry, cell differentiation counts, molecular biology and measurements of inflammatory mediators in collected samples. Because the project is carried out in a translational research environment, the applicant will have the possibility to perform experiments on human tissues or cells. The aim is to enhance existing models and establish new practices, independently and in collaboration with co-workers.

Last Application Date: 01.Jun.2022

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20. Postdoctoral studies in Alzheimer’s Disease

Summary of Postdoctoral Fellowship:

The postdoctoral position is for lab (experimental) based research and the postdoctoral fellow will be working in the research group of Professor Agneta Nordberg ‘Translational Molecular Imaging Lab’ which consists of multi-disciplinary team of experienced researchers and clinicians working at the forefront of translational dementia research. The research group has a translational approach using both in vitro and in vivo molecular brain imaging techniques, and our aim is to explore the complex pathophysiological features of neurodegenerative diseases, with a strong focus on Alzheimer’s disease (AD) but also other neurodegenerative disorders, to develop novel diagnostic markers and drug targets for early intervention in disease pathophysiology.

Last Application Date: 01.Jun.2022

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21. Postdoctoral Researcher in Reproductive Endocrinology and Metabolism

Summary of Postdoctoral Fellowship:

The group combine in vivo and in vitro clinical and mice experiments with single cell multiomic sequencing of collected tissues to investigate epigenetic communication between germ cells, serum and somatic tissues aiming to identify molecular mechanisms underlying PCOS transmission to subsequent generations. The postdoctoral applicant is expected to lead a project of single-cell sequencing of human tissue. The applicant will also be involved in mice projects investigating how transgenerational transmission of PCOS occurs by dissecting molecular mechanisms of epigenetic inheritance and causal links.

Last Application Date: 01.Jun.2022

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22. Postdoctoral researcher in Neuroimmunology and Alzheimer´s disease

Summary of Postdoctoral Fellowship:

We are looking for an enthusiastic and highly motivated scientist who is interested in working in a multi- disciplinary team at the forefront of translational Alzheimer’s disease (AD) research. Our group aims to use encapsulated cell (EC Biodelivery) implants releasing nerve growth factor (NGF) to support degenerating cholinergic neurons in patients with AD leading to a disease-modifying/curative therapy. In relation to this, we want you to investigate the involvement of immunological processes with AD pathology and therapy outcome with a focus on the cholinergic system. Or conversely, whether the therapy modulates immune response.

Last Application Date: 31.May.2022

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23. Research Specialist in suicide prevention

Summary of Postdoctoral Fellowship:

The Department of Learning, Informatics, Management and Ethics (LIME) carries out research and offers education with the aim to promote the practical implementation of research findings and newly acquired knowledge in the field of public health and healthcare. The department has two university-wide areas of activity – pedagogical development and support, as well as research, education and counseling in the field of healthcare and research ethics. It is an exciting work environment where research and education are in focus. We are now looking for a full-time Research specialist in the field of suicide prevention who can take part and support our suicide preventive activities in Sweden and Internationally.

Last Application Date: 31.May.2022

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24. Postdoctoral studies in tumor immunology (scholarship)

Summary of Postdoctoral Fellowship:

The main objectives of the Department of Oncology-Pathology are basic, translational and clinical research and educational activities related to cancer. Approximately 300 people from over 40 nations are currently working at the department. More than 30 research groups with various cancer research profiles are involved and there is around 120 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians. Research group: The Department of Oncology-Pathology is searching for a postdoctoral fellow to work on gene expression programs governing macrophage phenotypes during tumor development. The position is with Dr. Rolny, who shares the lab Dr. Larsson at SciLife Lab, Solna, KI. The two groups encompass wet-lab and dry-lab knowledge that spans from state-of-the-art molecular biology to complex animal tumor models and advanced bioinformatic analysis of large data sets.

Last Application Date: 31.May.2022

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25. Postdoctoral Researcher in experimental psychology

Summary of Postdoctoral Fellowship:

The Department of Learning, Informatics, Management and Ethics (LIME) works in several strategic areas that are important for improving human health. We focus on research, development and education in medical education, ethics, informatics, medical management, statistics and prevention. It is an exciting work environment where research and education are in focus.

Last Application Date: 31.May.2022

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26. Postdoctoral Researcher in the role of the intestine in cardiometabolic disease

Summary of Postdoctoral Fellowship:

Cardiometabolic disease is to a large part underlying the vast increase in non-communicable diseases observed in recent years; particularly relevant for the current project are the components obesity, insulin resistance, non-alcoholic fatty liver disease(NAFLD)/steatohepatitis (NASH) and atherosclerotic cardiovascular disease. The intestinal compartment is the first line of contact with food and serves as integrator and relay for signals derived from the interplay of microbiota, food, different epithelial cell types and immune cells. The current project aims to mechanistically explore how these interactions impact cardiometabolic disease and to delineate the signalling pathways involved. The intended experiments span from cell culture to in vivo models of disease (including work with germ-free models). Results from multiple layers of information derived from bulk RNA and single cell sequencing together with proteomics and metabolomics will be integrated to discover and map novel signaling pathways. These approaches are complemented with lipid biochemistry and in vivo characterization of metabolism using dynamic tests.

Last Application Date: 31.May.2022

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27. Postdoctoral researcher in particle toxicology

Summary of Postdoctoral Fellowship:

The aim of the research at the unit Metals and Health is to identify toxic effects of metals in the general and in the work environment, to understand causal relationships between metal exposure and various diseases, and how susceptibility factors influence these relationships. We also study mechanisms of particle toxicity with a focus on metal and combustion-generated particles. We work both in vitro and using molecular epidemiology approaches. We now search for a postdoctoral researcher with competence in particle toxicology.

Last Application Date: 31.May.2022

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28. Postdoctoral studies in Immunology

Summary of Postdoctoral Fellowship:

The research group of Dr. Magdalena Paolino, included in the Department of Medicine, Solna, at the Bioclinicum building of the Karolinska University Hospital. With our research, we aim to go all the way from animal genetics to therapy, and we strive to have important implications for human health and disease treatment. The Bioclinicum provides an open and international research environment, top-notch in-house infrastructure, and access to daily seminars and lectures by world-leading scientist. Karolinska Institutet is one of the world’s leading medical universities and hold the largest range of medical education in Sweden.

Last Application Date: 31.May.2022

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29. Postdoctoral scholarship positions in Computational Structural Biology

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoctoral researcher in structural bioinformatics to join a new and growing research team dedicated to understand the effects of cancer mutations from a structural and dynamical perspective. The candidate is expected to participate in collaborative efforts to develop a workflow for multiscale screening of cancer mutations, integrating and developing different coarse-grained and atomistic simulation methods. Advanced knowledge in structural bioinformatics and proven experience with molecular simulation tools (GROMACS, CHARMM, etc) and/or multiscale and coarse-grained approaches is a prerequisite. The applicant must be well acquainted with programming & scripting languages common in the biomolecular simulation field. Previous experience with protein simulations, knowledge of complimentary structural analysis techniques (Network Analysis, PCA, etc) and additional molecular modelling methods (molecular docking, virtual screening, etc) will be highly valued.

Last Application Date: 30.May.2022

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30. Postdoctoral Researcher in disabling occupational injuries – rehabilitation

Summary of Postdoctoral Fellowship:

We are looking for two postdocs who will work in one or more research projects in disabling occupational injuries (accident, illness or disability/discomfort caused by the work). The positions are advertised and appointed centrally, which means that the successful candidate together with Karolinska Institutet will find a suitable department and research group to work with. The work will be planned together with a research group leader. The first two years are fully funded, with a possible extension within consultation with research group leaders and the department.

Last Application Date: 30.May.2022

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31. Postdoctoral Researcher in disabling occupational injuries – prevention

Summary of Postdoctoral Fellowship:

We are looking for two postdocs who will work in one or more research projects in disabling occupational injuries (accident, illness or disability/discomfort caused by the work). The positions are advertised and appointed centrally, which means that the successful candidate together with Karolinska Institutet will find a suitable department and research group to work with. The work will be planned together with a research group leader. The first two years are fully funded, with a possible extension within consultation with research group leaders and the department.

Last Application Date: 30.May.2022

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32. Postdoctoral Researcher in radiology and experimental Surgery

Summary of Postdoctoral Fellowship:

To be a successful candidate, you have experience from evaluating liver function by MRI and you have passed the necessary animal courses to perform animal research in Sweden. You have experience in RIS and PACS and you have previously performed research using radiomics and/or artificial intelligence and deep learning. You have fluent knowledge in speaking and writing English. We are looking for a structured candidate with high social skills, who is able to work independently. We value personal qualities in the selection of candidates.

Last Application Date: 27.May.2022

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33. Postdoctoral studies in in innate lymphoid cell immunobiology (scholarship)- extended application time

Summary of Postdoctoral Fellowship:

Using the latest techniques in metabolic profiling and single-cell sequencing the candidate will map the metabolic profiles of human ILCs across a range of tissues and inflammatory conditions. The candidate will also perform multi-parameter flow cytometry, ELISA, Seahorse, siRNA/ lentiviral ‘knock-downs’ and in vitro cultures using ILCs and T cells extracted from tissue samples. The individual will work in a multi-disciplinary team environment meaning excellent communications skills are essential. It is expected that the postdoctoral researcher will eventually supervise students and other researchers, as well as contribute to common lab duties.

Last Application Date: 25.May.2022

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34. Postdoctoral Researcher in oral and intestinal mucosal immunology

Summary of Postdoctoral Fellowship:

The nasopharynx and the oral mucosa are the gate of first encounter between environmental elements and the gastrointestinal tract. The complexity of different and well differentiated mucosal tissues, as well as the presence of distinct microenvironments, make the oral cavity a unique mucosal barrier that has been largely understudied. It is known that the oral cavity could be a mirror of systemic diseases, such as IBD and CRC, and that the disturbances in the oral immune homeostasis could be linked with systemic illness. However, the molecular and cellular mechanisms behind those interactions and its consequences in health or disease are still unresolved. The goal of this project is to elucidate how the disruption of the immune homeostasis at the oral or gut mucosal barriers could influence each other, and to propose the potential mechanisms behind those interactions.

Last Application Date: 25.May.2022

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35. Post-doctoral researcher in Biomaterials and Regenerative Medicine

Summary of Postdoctoral Fellowship:

A post-doctoral researcher position is available in the group of Professor Molly Stevens in the Division of Biomaterials at the Department of Medical Biochemistry and Biophysics (MBB). The successful applicant will join a multidisciplinary research team with a translational profile in biomaterials and tissue engineering, and should have expertise in developing and characterizing novel lipid nanoparticle formulations for healthcare applications. The successful candidate will be involved in contributing to translational projects at the interface between biomaterials science, chemistry and biology. The candidate will work on the development and characterization of composite materials with controlled architecture, composition and biological activity of a range of healthcare applications. Focus of the research will be in the field of soft matter applications for healthcare. In particular, the role entails the design, preparation and characterization of a range of lipid nanoparticle formulations for drug delivery applications.

Last Application Date: 24.May.2022

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36. Postdoctoral researcher in psychology with a focus on inequalities in mental health

Summary of Postdoctoral Fellowship:

We are currently looking for a postdoctoral researcher who will be working on several research projects in a research group lead by Richard Bränström with a focus on inequalities in health and minority stress. The position entails participation in, planning, and conducting research studies that aim to identify risk factors and mechanisms of mental health in minority groups based on sexual orientation and gender identity. The position provides an excellent opportunity for transition to career independence and an engaging and international research environment where you will be able to contribute to internationally leading research.

Last Application Date: 24.May.2022

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37. Postdoctoral studies in regeneration

Summary of Postdoctoral Fellowship:

The Simon research group is studying regeneration processes in aquatic salamanders. Natural examples of regeneration, such as salamanders, may unravel novel strategies for cell replacement of damaged or lost tissues. We study regeneration mechanisms in an aquatic salamander, the newt, which has the widest repertoire of regenerative abilities among tetrapods. During the past decade, our laboratory has developed several methods, which has made these outstanding questions experimentally tangible. We place our findings on newt regeneration into an evolutionary context and test our results in a variety of mammalian in vivo and in vitro assays. The main target tissue of our investigations in the context of limb regeneration is skeletal muscle. Skeletal muscle can contribute to limb regeneration in two ways, either by activation of quiescent stem cells or by dedifferentiation of differentiated muscle fibers. By various cell tracking strategies, we try to compare these two processes to each other in terms of their relative contribution to the limb. We also characterize molecular processes involved in the generation of limb progenitors from skeletal muscle.

Last Application Date: 23.May.2022

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38. Postdoctoral Researcher in chronic pain research

Summary of Postdoctoral Fellowship:

We invite applications for a joint post doc position in Prof Camilla Svensson’s team that explores cellular and molecular mechanisms underlaying chronic pain states. The position will be placed in the Department of Physiology and Pharmacology at the Karolinska Institutet, which has a collegial, international and dynamic research environment. The Svensson lab is part the Center for Molecular Medicine (CMM) located on the premises of the Karolinska Hospital. We offer an exciting, open, and collaborative research work environment and project, where you can make a difference.

Last Application Date: 20.May.2022

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Karolinska Institute has huge a campus in Sweden and widely known as for its contribution in top notch education and research. The contribution of Karolinska Institute is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc..

1. Postdoctoral studies in systems biology of mRNA translation (scholarship)

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. The focus for the project will be to use biostatistics and bioinformatics to understand how mRNA translation is organized and orchestrated in health and disease.

Last Application Date: 05.May.2022

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2. Postdoctoral studies of mRNA translation in cancer

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. Although the focus for this project will be to use advanced molecular biology approaches to study mRNA translation in cancer, there will also be opportunities to learn analysis of large scale data sets.

Last Application Date: 05.May.2022

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3. Postdoctoral Researcher in Metabolic Engineering in RNA virus infection

Summary of Postdoctoral Fellowship:

Are you interested to learn how our immune system interacts with viruses and can we explore virus weakness to eliminate it? We are looking for a Post-Doctoral researcher for our research theme, the correlates of immune protection against RNA viruses, who will work mainly to understand the immune-metabolic modulation during acute or chronic viral infection. A major focus of the work will be on virus-host cell interaction and to determine the signaling pathways that drive virus-induced disease biology in HIV-1 and SARS-CoV-2. The ideal candidate will possess exceptional skills in virology, multi-color flow cytometry, and/or cell biology. Preference will be given to those who worked with the BSL3 viruses and immune modulation of cellular pathways in the cell lines and primary cells. Expertise in the field of metabolism, loss-of-function screens and reverse viral genetics including CRISPR-Cas9 would represent a major advantage.

Last Application Date: 30.Apr.2022

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4. Postdoctoral Researcher in NK cell biology

Summary of Postdoctoral Fellowship:

The Malmberg Lab is located in Stockholm/Sweden and Oslo/Norway and currently consists of 24 people. We are now looking for a highly motivated post-doc with an interest in molecular immunology and experimental immunotherapy. The project concerns the differentiation of human NK cells from inducible pluripotent stem cells (iPSC), with a particular focus on directed differentiation into effector cells with desired phenotype and function. One central element is to use our synthetic biology platform to improve the persistence and boost the cytotoxic potential of iPSC-derived NK cells. This project is carried out in close collaboration with our US-based industrial partner Fate Therapeutics and the Malmberg Lab at Oslo University Hospital.

Last Application Date: 30.Apr.2022

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5. Postdoctoral studies in Central Nervous System Regeneration after Spinal Cord Injury

Summary of Postdoctoral Fellowship:

Our lab investigates stromal scar formation and its impact on axonal regeneration and functional recovery following spinal cord injury. We discovered a new population of perivascular cells, called type A pericytes, as the source of fibrotic scar tissue (Göritz et al., Science, 2011) and identified pericyte-derived scar formation as a therapeutic target to achieve axonal regeneration and functional recovery following spinal cord injury (Dias et al., Cell, 2018). Recently, we showed that fibrotic scarring by perivascular cells is a conserved mechanism in the adult mammalian CNS (Dias et al., Nature Com., 2021). The intended project will test different strategies to interfere with fibrotic scarring to enhance axonal regeneration and functional recovery following spinal cord injury.

Last Application Date: 30.Apr.2022

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7. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (5)

Summary of Postdoctoral Fellowship:

We recently demonstrated that glutamine levels are lower in white adipocytes from obese compared to lean subjects and that this leads to white adipose tissue (WAT) inflammation (Petrus, Lecoutre et al, Cell Metabolism, 2020). Our new preliminary data in human and murine WAT, reveal that these changes are associated with decreased expression of Glutamine Synthase (GS, encoded by GLUL) and increased expression of glutaminase (GLS, encoded by GLS), the two enzymes governing glutamine metabolism. This suggests that glutamine turnover is a major determinant of adipocyte function. To further dissect the pathophysiological role of our observations in vivo, we have generated adipocyte-specific Gls and Glul knockout mice where we will study the effects of different perturbations on WAT and whole body metabolism. These analyses will be complemented by state-of-the-art mechanistic studies in human adipocytes in which we for instance will perform metabolic flux analyses following CRISPR/Cas9-mediated engineering of the glutamine pathway.

Last Application Date: 30.Apr.2022

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8. Postdoctoral Researcher in Metabolic Engineering in RNA virus infection

Summary of Postdoctoral Fellowship:

Are you interested to learn how our immune system interacts with viruses and can we explore virus weakness to eliminate it? We are looking for a Post-Doctoral researcher for our research theme, the correlates of immune protection against RNA viruses, who will work mainly to understand the immune-metabolic modulation during acute or chronic viral infection. A major focus of the work will be on virus-host cell interaction and to determine the signaling pathways that drive virus-induced disease biology in HIV-1 and SARS-CoV-2. The ideal candidate will possess exceptional skills in virology, multi-color flow cytometry, and/or cell biology.

Last Application Date: 30.Apr.2022

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9. Postdoctoral Researcher in NK cell biology

Summary of Postdoctoral Fellowship:

Our research group seeks to develop new strategies for cell-based immunotherapy based on insights into the functional regulation of NK cells. Through partnerships with leading NK cell groups in Europe and the US, as well as the biotech industry we design and run clinical trials for patients with cancer. At the Center for Infectious Medicine at the Karolinska Institutet you will find a stimulating research environment with the vision to be a world-leading translational research center within immunology.

Last Application Date: 30.Apr.2022

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10. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (1)

Summary of Postdoctoral Fellowship:

Many immune mediated diseases including type-I diabetes are linked to perturbed immune system development or skewed immune-microbiome relationships early in life. Most information on immune development to date stems from mouse models or cord blood, but neither of these can account for environmental exposures in human newborns. Our group has performed a first longitudinal study of immune development in human newborns using modern systems immunology methods and revealed immune-microbe differences with possible relevance to diseases such as type I diabetes. Microbial composition is influenced by mode of delivery, feeding and antibiotic exposure and the microbiome evolves through an ordered sequence of events.

Last Application Date: 30.Apr.2022

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11. Post doc position with a focus on host-microbe interplay in health and disease

Summary of Postdoctoral Fellowship:

The employment has a focus on research. The postdoctor will conduct research within several projects, focusing on the impact of host-microbiome interplay during immune homeostasis and dysregulation, using human data and data from experimental models. The main task of the postdoctor will be bioinformatics analysis of 16S and metagenomic data and their integration with environmental exposure data, clinical data and other OMICs layers.

Last Application Date: 20.Apr.2022

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12. Postdoctoral Researcher in RNA Biology

Summary of Postdoctoral Fellowship:

Dr. Linxian Li’s Laboratory has long interests in developing novel therapeutics for clinical applications. Committed to translating new technology for medical use, the Li group focuses on using chemical synthesis, biological tools and artificial intelligence to develop mRNA therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in RNA biology.

Last Application Date: 24.Apr.2022

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13. Postdoctoral Researcher in Enzyme Engineering

Summary of Postdoctoral Fellowship:

Dr. Linxian Li’s Laboratory has long interests in developing novel therapeutics for clinical applications. Committed to translating new technology for medical use, the Li group focuses on using chemical synthesis, biological tools and artificial intelligence to develop mRNA therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in enzyme engineering.

Last Application Date: 24.Apr.2022

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14. Postdoctoral fellow in projects on person-centered care transition after stroke

Summary of Postdoctoral Fellowship:

We are looking for a postdoctoral fellow who will work on a project on person-centered care transition after stroke and TIA. The project is called Missing link and is based on the research group Neuroepidemiology and health care research. The project aims to evaluate a newly developed care transition where the patient should feel safe, involved and well-informed through the care transition in connection with discharge from hospital after stroke and TIA. The project is a collaboration between people with stroke, health and medical staff and an interdisciplinary project group of researchers at Karolinska Institutet. The group includes physiotherapists, sociologists, nurses, doctors and pharmacists. The project team is currently conducting a feasibility study to evaluate the feasibility of the intervention.

Last Application Date: 2022-04-26

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15. SRP Diabetes Postdoctoral Fellowship Programme at Karolinska Institutet

Summary of Postdoctoral Fellowship:

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project, mentored by world-leading researchers in the field of diabetes. To increase coherence around the Fellowship programme, several events will be held throughout the year such as high-profile lectures, symposia, etc. which the fellows will attend. The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2022, though some flexibility with the start date might be possible.

Last Application Date: 30.Apr.2022

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16. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (2)

Summary of Postdoctoral Fellowship:

We are interested in understanding how skeletal muscle insulin sensitivity is altered, both in response to pathology such as type diabetes, and as a response to physical exercise. This fellowship programme is focused on the role of miRNAs in this regard, in particular miRNAs in small extracellular vesicles (also called exosomes. We have previously identified several miRNA which are dysregulated in skeletal muscle in subjects with type 2 diabetes, and which contribute to changes in metabolism and insulin signalling, including let7 (Jiang et al., 2013), miR-29 (Massart et al., 2017) and mIR20b (Katayama et al., 2018). Since miRNAs are able to target multiple genes simultaneously, miRNAs provide a potential mechanism for efficiently modulating a whole pathway to change or alter the functional properties in specific target tissues.

Last Application Date: 30.Apr.2022

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17. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (3)

Summary of Postdoctoral Fellowship:

Comorbidities of type II diabetes (T2D) are major health concerns worldwide, including peripheral artery disease (PAD). PAD lowers blood flow to the lower limb, causing muscle ischemia and dysfunction and reduced exercise tolerance. Functionality of limb skeletal muscle is a key component for determining morbidity and mortality risk in patients with PAD. Interventions that improve distal arterial pressures (ie. bypass surgery) generally fail to normalize the structural and functional abnormalities of muscles, which point towards pathophysiological mechanisms inside the skeletal myofibers that reduce overall muscle function. Despite serious muscle abnormalities, the field is lacking molecular understanding of PAD-induced muscle dysfunction.

Last Application Date: 30.Apr.2022

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18. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (4)

Summary of Postdoctoral Fellowship:

The postdoctoral project will focus on pharmacoepidemiological research and causal inference methods using data from national health, population and quality registers. The aim is to investigate the impact of socioeconomic factors on antidiabetic medications (ADM) use, discontinuation and type 2 diabetes (T2D) consequences such as cardiovascular diseases, kidney failure and retinopathy. The overarching purpose of the project is to identify differences in patterns of ADM use across socioeconomic groups, which will ultimately provide evidence for the development of targeted interventions for treatment management and guidelines increasing awareness about high-risk groups among the vulnerable population of T2D patients.

Last Application Date: 30.Apr.2022

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19. Postdoctoral studies Targeting the Ubiquitin-Proteasome System with Small Molecules

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated and skilled scientist with experience in drug development and/or the ubiquitin-proteasome system or autophagy. Advanced skills in molecular biology, cell biology and biochemistry are important assets for this project. A background in chemistry and/or bioinformatic analysis can also be advantageous. Other helpful skills are experience with the cell-based assays and fluorescence microscopy. Good knowledge of both spoken and written English is a requirement.

Last Application Date: 30.Apr.2022

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20. Postdoctoral fellow with a focus on risk assessment of chemicals

Summary of Postdoctoral Fellowship:

We are looking for a motivated Postdoctoral fellow who has a doctorate in regulatory toxicology or related disciplines. You will work with great independence in project form together with other researchers at the unit for integrative toxicology. You are responsible for developing the work with dose-response analysis in relation to data from a number of different studies – from experimental models (in vitro and in vivo) to epidemiology. You present the results in the form of scientific articles and at conferences, but you are also a driving force in building a network of contacts at Swedish and international authorities and contribute to the unit’s teaching activities.

Last Application Date: 2022-04-08

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21. Postdoc Researcher in Translational Melanoma Research

Summary of Postdoctoral Fellowship:

We are looking for a postdoc who is curious and eager to solve biological questions with focus on translational melanoma research. Specifically, we are interested in understanding how the inflammatory response in the tumor microenvironment affects tumor progression and response to melanoma therapies. The current position offers outstanding opportunities to develop as a researcher in an innovative and stimulating research environment by combining, together with a dedicated group of scientists and clinicians where the postdoc will contribute with her/his expertise.

Last Application Date: 11.Apr.2022

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22. Postdoctoral Researcher in protein biochemistry and biotechnology

Summary of Postdoctoral Fellowship:

This project is focused on protein engineering and recombinant expression and purification of silk proteins, and functionalized variants thereof, in prokaryotic hosts, with subsequent biochemical and biophysical characterization. You will formulate different materials and do mechanical, structural and functional characterization of these. The successful candidate is expected to have a large interest in biotechnology and protein biochemistry and is expected to enjoy practical lab work and independently generate and analyze data. The candidate will supervise doctorial students and master students in the lab. We work in collaboration with other groups and very interdisciplinary, which demands the applicant to be independent, creative, have a positive attitude and be collaborative. The candidate will work primarily at KI campus Flemingsberg, but is also expected to travel to and work in the lab at SLU in Uppsala.

Last Application Date: 12.Apr.2022

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23. ONE Postdoctoral Researcher in chemical and genetic screens

Summary of Postdoctoral Fellowship:

We are currently looking for a postdoctoral scientist to join our team with a Ph.D. in Cell Biology, Molecular Biology, Biochemistry, or other relevant fields. We are specifically looking for a highly motivated scientist that is looking to complement his/her skills with experience in large chemical and genetic screens, and that has the capacity to independently develop a scientific research project that relies mostly on cell and molecular biology technologies. In addition, it is expected that the candidate will help in the training of junior group members. Other valuable skills such as writing or presenting capacities or social skills will also be appreciated.

Last Application Date: 13.Apr.2022

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24. Postdoctoral researcher in skeletal stem cells

Summary of Postdoctoral Fellowship:

This opening is focused on skeletal growth and the mechanisms of its maintenance. The successful candidate will be expected to plan and conduct experimental research to reveal basic mechanisms relating to skeletal disorders arising from childhood cancer treatments. More specifically, duties will include collecting and analysing human tissues, maintaining a colony of mice, processing and analysing murine samples. Methodologies include confocal microscopy, histological and histochemical staining, immunofluoresence, in situ hybridisation and RNAseq. The candidate is expected to drive their project forward and actively follow the scientific literature.

Last Application Date: 14.Apr.2022

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25. Postdoctoral Researcher in project focused on dopamine neuron maintenance in Parkinson’s disease

Summary of Postdoctoral Fellowship:

The lab’s focus is on the development and maintenance of dopamine neurons within the ventral midbrain. We are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have relevance for regenerative medicine and neurodegeneration in relation to Parkinson’s disease and other brain disorders. We are using mouse genetics and other methods including single cell RNA sequencing in our studies. In collaborative projects we also focus on regenerative strategies such as stem cell therapy, and on the maintenance of dopamine neurons in the human brain.

Last Application Date: 14.Apr.2022

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26. Postdoctoral Researcher in Molecular and Translation Lung Cancer Research

Summary of Postdoctoral Fellowship:

We are seeking a Postdoctoral Researcher (Scholarship) with an interest in lung cancer biology/therapy. You should hold great prior knowledge in tumor biology and it is preferred that you already are familiar with extracellular vesicles (EVs) research. When joining us you will work in a multidisciplinary environment, close to frontline preclinical/translational/clinical lung cancer research but also in context of radiation therapy as well as with our partners on microchip technology for EVs characterization.

Last Application Date: 15.Apr.2022

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27. Postdoctoral researcher to study synergistic effects between DNA damaging cancer therapeutics and targeted agents for an industrial collaboration

Summary of Postdoctoral Fellowship:

Cancer is often characterized by genome instability which is one of the enabling characteristics of cancer. Along the progression of cancer, mutations occurring in the genome maintenance and surveillance systems endanger the integrity of the genome. This genome instability results in new mutations and genomic rearrangements driving cancer progression via selection of favourable phenotypes. However, genomic instable cancer cells are more vulnerable to DNA damage than non-malignant cells since their DNA repair machinery often is deficient. This cancer cell vulnerability, along with the high proliferation rate of cancer cells, enables the usage of DNA damaging cancer treatment, such as ionizing radiation and chemotherapy, which have been used in cancer treatment for nearly a century.

Last Application Date: 18.Apr.2022

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28. Postdoctoral Researcher in Risk and Resilience in Neurodevelopmental Conditions using the ICF system

Summary of Postdoctoral Fellowship:

We are seeking a postdoctoral researcher with a strong passion for conducting research that strives to contribute to the quality of life and mental wellbeing of individuals with Neurodevelopmental Conditions. As part of a European consortium – Risk and Resilience in Developmental Diversity and Mental Health (R2D2-MH) – we are conducting research which aims to improve the mental health outcomes of young people with these challenges. The postdoctoral position will examine the factors related to risk and resilience for adverse health and psychosocial outcomes in by developing International of Classification of Functioning (ICF) core sets for risk and resilience in this population. In addition, the postdoc interacts with researchers in the European Consortium and contributes to other work packages investigating resilience.

Last Application Date: 18.Apr.2022

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29. Postdoctor in Immunology

Summary of Postdoctoral Fellowship:

A postdoctoral research position is now available in the laboratory of Immunology and Oncology led by Dr Lisa Westerberg. The laboratory is located in the top modern Biomedicum building with shared infrastructure for advanced technology platforms and built for interdisciplinary collaborations. Ongoing research is focused on understanding the molecular mechanisms in development of immunodeficiency diseases with high incidence of autoimmunity and cancer.

Last Application Date: 19.Apr.2022

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