46 Postdoctoral Fellowships at University of Pennsylvania, Pennsylvania

Are you holding PhD degree and looking for Postdoctoral Fellowships? University of Pennsylvania, Pennsylvania inviting application for multiple Postdoctoral Fellowships. University of Pennsylvania is one of the largest university in the world with thousands of employees, students, and research scientists are involved in the innovation of science and technology daily.

University of Pennsylvania has huge a campus in Pennsylvania, USA and widely known as for its contribution in top notch education and research. The contribution of University of Pennsylvania is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc..

1. Post-doc in Translational Chronobiology

Summary of Postdoctoral Fellowship:

The Weljie Lab in the Department of System Pharmacology and Translational Therapeutics at the University of Pennsylvania is seeking multiple highly motivated and independent post-doctoral fellows to help drive our program in quantitative metabolic profiling in chronobiology and translational research. Applicants with a wide variety of previous training are encouraged to apply. The focus of their work will be investigation of sleep and circadian biology as they relate to metabolism. Our lab applies analytical methods using mass spectrometry (LC-MS, LC-MS/MS, mass spec imaging and nuclear magnetic resonance, NMR) for comprehensive metabolite profiling and implementation of data analysis pipelines to a variety of model and clinical problems, including Drosophila, mice, and human samples.

Last Application Date: Open Until Filled

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2. Bioinformatics Research Position

Summary of Postdoctoral Fellowship:

The ITMAT Bioinformatics Laboratory is a bioinformatics research facility that supports the research efforts of over 1,500 laboratories at the University of Pennsylvania. We are not however a service or a core, we do not perform bioinformatics for fee, instead we conduct independent research on methods development and evaluation, and we collaborate on specific projects with select collaborators. We are particularly interested in all things transcriptomics, including data simulation. Our primary collaborators are in Pharmacology and Genetics, but we also collaborate with the biomedical community in general. Our postdocs should be oriented towards an academic career at the faculty level.

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3. Post Doc Fellow – Epigenetics

Summary of Postdoctoral Fellowship:

Post Doctoral Fellow positions are available in the laboratory of Dr. Jennifer Kalish, at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the CHOP/Penn campus that includes multiple areas of epigenetics, cancer, genetics, and molecular biology. We are located in the new Colket Translational Research Building as part of the Division of Human Genetics in the Department of Pediatrics and the Center for Childhood Cancer Research (CCCR). The lab is also part of the Penn Epigenetics program. The lab’s research focuses on the transition between normal growth, overgrowth and cancer using human-cell based model systems and patient samples to study epigenetic causes of abnormal growth and cancer. We are interested in the infection points between normal growth and the transition to cancer to understand how they reveal insights into fundamental epigenetic and cellular mechanisms. We are particularly interested in how cancer predisposition syndromes contribute to the genetic and epigenetic set up for cancer. The laboratory work is part of a larger translational research program in which patient samples and clinical data are collected through a patient registry.

Last Application Date: Open Until Filled

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4. Postdoctoral Position in Transcriptional Regulation in Hematopoiesis and Leukemia

Summary of Postdoctoral Fellowship:

A full-time postdoctoral position is available in the Paralkar Lab in the Division of Hematology-Oncology and the Abramson Family Cancer Research Institute at the University of Pennsylvania for an NIH-funded project to study transcription and chromatin regulation in hematopoiesis and leukemia. Transcription factors and chromatin-binding proteins regulate the transcription of coding and noncoding RNAs to orchestrate cellular transcriptomes and proteomes. The rate of transcription of ribosomal RNAs, the most abundant RNA in the cell, shows substantial variation across normal and malignant cell types in many organ systems, including in hematopoiesis, but little is known about its regulation in cell-type-specific contexts. The Paralkar Lab has identified that numerous hematopoietic and leukemic transcription factors bind ribosomal DNA (rDNA), and their regulation of rRNA transcription has implications for both normal and leukemic hematopoiesis.

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5. A postdoctoral position to design and perform research in equine sperm capacitation

Summary of Postdoctoral Fellowship:

A postdoctoral position to design and perform research in equine sperm capacitation, oocyte maturation, intracytoplasmic sperm injection, embryo culture and vitrification, and/or other aspects of equine assisted reproduction. Participate in the research and clinical embryo production procedures in the laboratory. Perform data collation and statistical analyses, prepare abstracts, presentations and research papers. Perform and assist with procedures with horses including transvaginal ultrasound-guided follicle aspiration; organize and maintain mare herd.

Last Application Date: Open Until Filled

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7. Postdoctoral Research Fellow Position in Neuroimaging in the Department of Radiology

Summary of Postdoctoral Fellowship:

A postdoctoral position for an MR physicist is available in the Division of Neuroradiology/Department of Radiology in the Cerebrovascular Lab (www.TheSongLabBrain.com) at the University of Pennsylvania. The position is to conduct research on multiplexed neuroimaging. We will use new deep learning-based processes that fuse multimodal images and create higher quality, data-rich medical images. Maximizing imaging data from each modality, we will then use machine learning to identify, validate and implement the use of neuroimaging biomarkers for neurologic disorders. This AI-fueled project will leverage the expertise of an interdisciplinary team to propel medical innovation towards more precise and personalized diagnostic strategies. The position requires focused expertise in the specific area of developing advanced MRI pulse sequences, image reconstruction/analysis methods and applying these techniques to neuroimaging for neurological disorders.

Last Application Date: Open Until Filled

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8. Postdoctoral fellow to engage in computational image analysis 

Summary of Postdoctoral Fellowship:

The Penn Image Computing and Science Laboratory (PICSL) and the Penn Alzheimer’s Disease Research Center (ADRC) are seeking to recruit a postdoctoral fellow to engage in computational image analysis research focused on studying variability of imaging-based biomarkers of Alzheimer’s disease. The postdoctoral fellow will be working with ADRC faculty to analyze unique in vivo and postmortem imaging datasets using novel image registration, segmenta-tion, morphometry, and machine learning techniques. Candidates should have completed (or be about to complete) a Ph.D. in a relevant field of study and have a strong interest in neurodegenerative disease research.

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9. Cancer Genetics Postdoctoral Position

Summary of Postdoctoral Fellowship:

The Maxwell Laboratory is seeking a highly motivated and creative postdoctoral fellow to understand the role of inherited TP53 mutations and interactions with the immune system in breast tumor development. The PI, Dr. Kara Maxwell, runs the Li Fraumeni Syndrome (LFS) Biobank at Penn Medicine, which ascertains patients with inherited mutations in the tumor suppressor TP53. The LFS biobank contains extensive clinical information, germline and tissue samples, peripheral blood mononuclear cells, and lymphoblastoid cell lines created from patients. Our studies have shown that certain hypomorphic TP53 mutations lead to high risks of breast cancer. Using knock-in breast cancer cell lines and patient derived lymphoblastoid cell lines, the postdoctoral fellow will characterize p53 pathway defects associated with these alleles.

Last Application Date: Open Until Filled

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10. Postdoctoral research fellow with expertise in patient-oriented and behavioral research

Summary of Postdoctoral Fellowship:

The Bradbury Lab in the Department of Medicine, Division of Hematology-Oncology and the Department of Medical Ethics and Health Policy at the University of Pennsylvania is recruiting a highly motivated postdoctoral research fellow with expertise in patient-oriented and behavioral research. Position is initially offered for one year – and can be extended up to at least three years contingent upon outstanding performance and program funding. Candidate can begin as early as January 2022. Available project within the Bradbury lab include several NIH funded translational genetic research studies focused on the clinical implementation of genetic medicine to promote the health of individuals, families and communities.

Last Application Date: Open Until Filled

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11. Postdoctoral fellowship position to study lung regeneration

Summary of Postdoctoral Fellowship:

The Morrisey Lab is an integrated team of postdoctoral fellows, physician-scientists, students, and researchers whose goal is to better understand the cellular and molecular etiology of lung disease and regeneration. We have an open postdoctoral fellowship position to study lung regeneration. The ideal candidate will have a Ph.D., M.D., or both with experience in genetic models of stem/progenitor cell development and activation after injury. Additional experience in organoid modeling of stem cell behavior, single cell genomic analysis, and imaging are an asset. Candidates should be willing to work in a team environment that is enthusiastic, collaborative, and supportive.

Last Application Date: Open Until Filled

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12. Two Post-Doctoral Scholar positions to study platelets and vascular biology

Summary of Postdoctoral Fellowship:

Two Post-Doctoral Scholar positions are available for NIH-funded studies on platelets and vascular biology. The Brass lab uses a combination of cell biology, mouse models, computational models, and in vivo imaging to answer basic and translational questions about hemostasis, thrombosis, cell signaling, and the role of platelets in maintaining vascular integrity. The lab exists within a vibrant community of investigators at Penn and Children’s Hospital of Philadelphia with shared interests (and research) in platelet, coagulation factor and vascular biology and is supported by a multi-investigator program project grant based at Penn. Participating laboratories meet weekly and share an NIH HLBI T32-funded training program.

Last Application Date: Open Until Filled

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13. Two postdoctoral researcher positions

Summary of Postdoctoral Fellowship:

Two postdoctoral researcher positions are available in the laboratory of Dr. Xiaolu Yang at the Perelman School of Medicine at the University of Pennsylvania. Our lab is interested in cancer, stemness, and neurodegeneration. The current projects focus on two areas: (1) The tumor suppressor p53, metabolism, and autophagy. We are interested in the regulation and functions of the preeminent tumor suppressor p53. Our results have revealed an important role for p53 in modulating metabolic pathways that are critical for biosynthesis and redox balance. We are investigating the function of p53 as both a sentinel and a regulator for metabolic activities.

Last Application Date: Open Until Filled

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14. Postdoctoral Fellow Cancer Chemical Biology

Summary of Postdoctoral Fellowship:

The Brady lab led by Dr. Donita Brady is part of the Department of Cancer Biology and the Abramson Family Cancer Research Institute in the Perelman School of Medicine at the University of Pennsylvania. We are currently recruiting three postdoctoral fellows to join our research program at Penn. Our research program at Penn is founded in a new paradigm in nutrient sensing and protein regulation, termed metalloallostery, where redox-active metals control kinase activity, and is advancing our knowledge in basic science and disease-focused areas. Our focus lies at the intersection of kinase signaling and copper (Cu) homeostasis with the goal of defining the mechanistic features of Cu-dependent kinases to target them in cancer via drug repurposing or development. The emergence of this new paradigm in nutrient sensing and protein regulation has established that Cu is a critical mediator of intracellular signaling, provided evidence for the existence of molecular mechanisms for sensing changes in Cu abundance, and expanded the contribution of Cu to cellular processes necessary for adaptation to nutrient scarcity.

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15. Postdoctoral fellow in molecular virology

Summary of Postdoctoral Fellowship:

Our collaborative team studies the molecular biology of human papillomaviruses (HPVs). Our goal is to understand the molecular mechanisms by which HPVs modulate host cell processes and cause cancer. Projects are available in several broad areas. We use molecular and cell biological techniques as well as computational biology, mass spectrometry, high-throughput screening approaches, and more to investigate HPV biology. For examples of our recent work, see PNAS (2019) 116:7033-7042 and eLife (2022) 11:e75466. The Perelman School of Medicine provides an outstanding environment for postdoctoral training. Our colleagues include world-class physicians and basic scientists. Penn is home to outstanding tumor virology laboratories, the Abramson Cancer Center, and the Tumor Virology Program. There are abundant opportunities for collaboration with these and other groups at Penn, and at neighboring institutions.

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16. Postdoctoral fellow to study taste receptor signaling

Summary of Postdoctoral Fellowship:

Funding is available for a postdoctoral fellow to study taste receptor signaling in innate immunity, specifically how G-protein coupled taste receptors activate antimicrobial responses in immune cells. Our lab uses a combination of live-cell and confocal imaging, biochemistry, and molecular biology approaches using primary human cells isolated from nasal surgical samples and cultured at air-liquid interface. A main focus of our lab is bitter taste receptors, which are expressed in many tissues beyond just the tongue, where they serve largely unknown roles. In the airway, bitter taste receptors detect bacterial products and activate calcium-driven innate immune responses. In macrophages, bitter taste receptors regulate phagocytosis through calcium and NO signaling.

Last Application Date: Open Until Filled

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17. Postdoctoral fellow to study epithelial signaling in innate immunity

Summary of Postdoctoral Fellowship:

Funding is available for a postdoctoral fellow to study epithelial signaling in innate immunity, specifically how G-protein coupled receptors activate antimicrobial responses in nasal and lung cells. Our lab uses a combination of live-cell and confocal imaging, biochemistry, and molecular biology approaches using primary human cells isolated from nasal surgical samples and cultured at air-liquid interface. A main focus of our lab is bitter taste receptors, which are expressed in many tissues beyond just the tongue, where they serve largely unknown roles. In the airway, bitter taste receptors detect bacterial products and activate calcium-driven innate immune responses.

Last Application Date: Open Until Filled

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18. Post Doctoral Fellow

Summary of Postdoctoral Fellowship:

The Dodge Translational Orthopaedic Research Laboratory at the McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery at the University of Pennsylvania is seeking an individual to fill a full time Research Post-Doctoral position. The position will be in part to support the research operation of Mechano Therapeutics a UPenn spinout company The position involves working with team of scientists comprised of Drs. George Dodge, Nick DePhillipo, Robert Mauck and Daeyeon Lee in our laboratories at the University of Pennsylvania and the Mechano Therapeutics lab at Pennovation Center. This is an exciting opportunity for the person that wants experience in developing new technology that spans both the basic science and practical aspects that are part of a rapidly emerging company. 

Last Application Date: Open Until Filled

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19. Postdoctoral Position in Regenerative Medicine

Summary of Postdoctoral Fellowship:

The department of Orthopaedic Surgery at the University of Pennsylvania, School of Medicine in Philadelphia is seeking exceptional candidates to fill a postdoctoral position in the laboratory of Dr. Foteini Mourkioti. The Mourkioti laboratory is interested in the fundamental aspects of how skeletal muscles and cardiac systems function as well as the practical aspects of manipulating these systems by using animal models and tissue engineering approaches for disease intervention. The experiments will include mouse work, surgical procedures, flow cytometry, cell culture, histological and live-imaging methods.

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20. Postdoctoral Fellow

Summary of Postdoctoral Fellowship:

The position calls for a highly motivated candidate with a strong background in neurobiology, molecular biology and/or cellular biology. Experience working with rodent models of glaucoma or retinal degeneration, electrophysiology, molecular and cellular neurobiology, gene editing with CRISPR/Cas9 expertise and in vitro cell culture experiments including stem cell or iPSC derived culture are desired. Good oral and written communication skills are required. Responsibilities include designing and conducting experiments, analyzing data, preparing and presenting research findings at meetings, helping to write scientific manuscripts, and applying for fellowships/grants.

Last Application Date: Open Until Filled

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21. Postdoctoral Fellowship in Vision Science

Summary of Postdoctoral Fellowship:

The Uyhazi and Bennett laboratories at the University of Pennsylvania are seeking a motivated postdoctoral fellow to join our team to investigate gene therapy and cell-based therapies for vision loss. Our goal is to use cutting-edge technology focused on photoreceptor regeneration to better understand the cellular and molecular biology of retinal degeneration and to develop novel therapies for blinding diseases. The ideal candidate will have a Ph.D., M.D., or both with experience in genetic mouse models, molecular biology, immunofluorescence staining, and microscopy. Additional experience in single cell data analysis, iPSC culture, and visual function testing is an asset. Candidates should be willing to work in a team environment that is enthusiastic, collaborative, and supportive.

Last Application Date: Open Until Filled

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22. Postdoctoral fellow

Summary of Postdoctoral Fellowship:

A Postdoctoral Researcher position is available for highly motivated applicant in the laboratory of Dr. Fiona Simpkins at the University of Pennsylvania. Our focus is understanding resistance mechanisms to targeted therapies such as DNA Damage Repair inhibitors (DDRi), understanding how to sequence DDRi with Immuno-Oncology (IO) drugs, and identifying biomarkers or response to these agents. We have developed a preclinical drug development program in the Ovarian Cancer Research Center with the goal of moving novel laboratory therapeutic discoveries into the clinic. We have developed >150 patient derived xenografts (PDX), patient derived organoid, and primary tumor cultures from ovarian and endometrial cancers. These PDX models minic the original tumor, thereby accelerating the translation of preclinical study results into clinical trials for patients.

Last Application Date: Open Until Filled

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23. Postdoctoral research fellow

Summary of Postdoctoral Fellowship:

A postdoctoral research fellow position is available in the laboratory of Dr. Kate O’Neill, at the University of Pennsylvania (Penn). Our lab is part of the rich scientific environment on the Penn/CHOP campus that includes expertise and research interest in cancer, reproductive medicine, epigenetics, stem cell biology and emerging technologies. We are located in the Biomedical Research Building as part of the Department of Obstetrics & Gynecology and Center for Research on Reproduction & Women’s Health (CRRWH). The lab’s research focuses on spatial ‘omics of the female reproductive tract, endometrial regeneration and implantation.

Last Application Date: Open Until Filled

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24. Molecular Cancer Biology

Summary of Postdoctoral Fellowship:

Two postdoctoral researcher positions are available immediately. The positions will be supported by grants from National Cancer Institute as well as non-federal research grants. The projects will focus on 1) epigenetic alteration and non-coding RNAs; 2) tumor immunology and adoptive T cell therapy; and 3) targeted and epigenetic therapy. Next generation sequencing, single cell analysis, knockout and transgenic animals and gene editing technologies will be used in these projects. Novel computational biology approaches and resources will be provided from our computational biology team in the lab (http://52.25.87.215/home/). The position requires experience in cellular and molecular biology, such as the experimental technology on molecular mechanisms that control malignant transformation, tumor progression and metastasis. Previous experience in tumor immunology, knock-out and transgenic animals, RNA biology, epigenetics, cancer biology and cancer genomics would be helpful. We are also welcome the candidates, who are trained in other fields such as developmental biology, genetics and genomics, to apply these positions.

Last Application Date: Open Until Filled

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25. Post-doctoral fellow

Summary of Postdoctoral Fellowship:

The Wexler Lab at the Department of Medical Ethics & Health Policy at the Perelman School of Medicine at the University of Pennsylvania is seeking a full-time postdoctoral fellow in neuroethics. This 12-month position will begin in fall 2022; there is a possibility for renewal contingent upon funding. The fellow will work on an NIH-funded project that utilizes sociological methods to study the ethical, legal, and social implications of neurotechnology. The post-doctoral fellow will be able to participate fully in the life of the Department, which is among the world’s leading centers of bioethics research and teaching. The fellow will have full access to the intellectual resources of the Penn community. There may be the potential for the fellow to obtain core training in bioethics by participating in a weekly bioethics proseminar led by the Division Chief.

Last Application Date: Open Until Filled

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26. Postdoctoral Fellow – Environmental Epidemiology

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position in Environmental Epidemiology is available in the Department of Biostatistics, Epidemiology, and Informatics (DBEI) at University of Pennsylvania Perelman School of Medicine. The candidate will be involved in NIH funded epidemiologic research projects which examine environmental toxicant exposure and reproductive, perinatal and pediatric health outcomes, including pregnancy outcomes, child neurobehavior, and child cardiometabolic endpoints and new epidemiological methods. The environmental toxicants of interest include endocrine disrupting chemicals, heavy metals, persistent organic pollutants, air pollution, and chemical mixtures.

Last Application Date: Open Until Filled

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27. Postdoctoral position in Cardiovascular Research

Summary of Postdoctoral Fellowship:

A postdoctoral fellow position is available in the Cardiovascular Institute of the University of Pennsylvania Perelman School of Medicine to perform basic-translational research focused on the coronary microvasculature. Coronary Microvascular Disease (CMVD) accounts for 30-50% of ischemic heart disease yet has been understudied in the past. We have developed novel methods to image the coronary microcirculation and uncover novel mechanisms of CMVD. This position focuses on using genomics, mouse models, novel mouse imaging, and cell and molecular studies on gene regulation to understand the pathogenesis of CMVD and develop novel therapeutic approaches.

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28. Post-doctoral fellow at CNDR

Summary of Postdoctoral Fellowship:

Post-doctoral position is available at the Center for Neurodegenerative Disease Research (CNDR) at the University of Pennsylvania for a motivated scientist that assumes responsibility for ongoing research projects focused on understanding the pathogenic mechanism/s of TDP-43 aggregation in Frontotemporal Lobar Degeneration (FTLD-TDP), Amyotrophic Lateral Sclerosis (ALS), and age-related dementias (LATE). We are also interested in translating basic molecular and biochemical insights with the ultimate goal of identifying mechanisms and potential therapeutic targets that will help slow the progression of these diseases. Under the direction/guidance of Dr. Sílvia Porta, the post-doc experience will serve to extend, refine and enhance skills necessary for professional and career development, and it will enable the individual to broaden her/his scientific background by acquiring new research capabilities.

Last Application Date: Open Until Filled

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29. Postdoctoral Researcher in Pharmacoepidemiology

Summary of Postdoctoral Fellowship:

Dr. Sean Hennessy, a clinical pharmacist and pharmacoepidemiologist, is PI of a National Institute on Drug Abuse-funded study entitled “Drug-Drug Interactions Involving Methadone and Buprenorphine”. This study will: i) perform high-throughput physiologically-based pharmacokinetic screening to predict the degree to which two-drug and three-drug combinations that include methadone or buprenorphine increase biological exposure to those agents; ii) perform high-throughput pharmacoepidemiologic screening of two-drug and three-drug combinations that include methadone or buprenorphine with regard to rate of emergency department presentation or hospitalization for opioid overdose and poisoning, opioid adverse effects, and cardiac arrest…

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30. Post doctoral fellow

Summary of Postdoctoral Fellowship:

Seeking a motivated curious individual to conduct research into the biological basis of fatigue. The experimental model systems we use include the nematode C. elegans and the mouse. Experience with these model systems is preferred. The projects in the lab are funded by the NIH and by the DOD.

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31. A full-time postdoctoral position is available in the Chou Lab

Summary of Postdoctoral Fellowship:

A full-time postdoctoral position is available in the Chou Lab in the Division of Hematology at the Children’s Hospital of Philadelphia and the University of Pennsylvania for an NIH-funded project to study and enhance in vitro generation of red blood cells from induced pluripotent stem cells (iPSCs) for transfusion medicine. Red blood cell (RBC) transfusion is one of the most common medical treatments, with over 10 million units transfused per year in the United States alone. There is a need for alternative sources of red cells for transfusion. In vitro generation of red cells is a major goal in the field of regenerative medicine but has been hampered by available methods and renewable cell sources for a sustainable supply. Moreover, the need for rare red cells for use as reagents to detect specific antibodies in transfused patients further fuels efforts for production of cultured red cells, especially those with “designer” red cell antigen phenotypes.

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32. Postdoctoral position in genetic and epigenetic of neurodevelopmental disorders

Summary of Postdoctoral Fellowship:

The Akizu lab seeks candidates for a Postdoctoral position in genetic and epigenetic mechanisms of pediatric neurodevelopmental and neurodegenerative disorders. The ideal candidate must be highly motivated and creative with strong ability to design and carry out experiments with a high level of independence. The successful candidate will work full time in one of our projects while also collaborating with other lab members and investigators in our institution and will be encouraged to apply for postdoctoral and career development fellowships, present posters and talks in scientifically relevant conferences, and contribute to manuscript writing and submission.

Last Application Date: Open Until Filled

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33. Post Doctoral Researcher

Summary of Postdoctoral Fellowship:

The Modzelewski Lab at the University of Pennsylvania Department of Biomedical Sciences School of Veterinary Medicine is recruiting postdoctoral researchers to join an exciting new NIH-NICHD funded project. Our work focuses on understanding the exciting and emerging role of retrotransposons in early development (and beyond). We are currently looking at how retrotransposons impact fertility and preimplantation development in mice but with comparative biology studies using various placental mammalian species to learn about human health and reproduction. The lab has two major but linked focuses: Developmental Biology and Genome Editing.

Last Application Date: Open Until Filled

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34. Postdoctoral fellow in human tumor immunology

Summary of Postdoctoral Fellowship:

We are seeking a highly devoted and enthusiastic PhD or MD/PhD scientist to join our group as a postdoctoral research fellow. He/She will be involved in investigating the role of the inflammatory myeloid cells in the tumor microenvironment and the cellular and molecular mechanisms by which tumor modulates their immune functions in cancer patients. Specifically, the researcher will investigate the role of the tumor-infiltrating macrophages and neutrophils in the regulation of tumor-specific T cell and NK cell responses in lung cancer patients. Also, He/She will investigate the ability of tumor-associated neutrophils and macrophages to regulate anti-tumor antibody-triggered immune responses.

Last Application Date: Open Until Filled

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35. Postdoctoral Position in Tumor & Radiation Oncology

Summary of Postdoctoral Fellowship:

The Koumenis and Minn labs in the Department of Radiation Oncology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, PA seek qualified and self-motivated candidates for a joint Postdoctoral Fellow position available immediately to study the molecular mechanisms underlying an exciting new radiation modality (“FLASH radiotherapy”). Our groups are well funded by large NIH grant and Foundation grants and by industry sponsored agreements. The two labs are part of a large Research Division comprised of 10 faculty and is well integrated within the Abramson Cancer Center. There are ample opportunities for training and career development, including mentoring on grant writing, career advice, networking and attendance and presentations national and international scientific meetings and symposia. Former graduate students and postdoctoral fellows trained in our labs currently hold faculty positions in academia and scientist positions in industry and in government agencies.

Last Application Date: Open Until Filled

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36. NIH/NIDA T32 Translational Addiction Research Fellowship Program at the University of Pennsylvania 

Summary of Postdoctoral Fellowship:

Post-doctoral applications are invited for training in the NIH-NIDA T32 Translational Addiction Research Fellowship Program within the Department of Psychiatry at the University of Pennsylvania School of Medicine. The translational emphasis of the program is reflected both in the didactics and mentoring structure, with each trainee receiving exposure both to preclinical and clinical science in addiction. The addiction research laboratories at Penn offer a wide range of training opportunities, including: brain PET and MRI imaging of vulnerabilities to relapse (e.g. heightened limbic response to drug cues; impaired decision-making, etc.), human laboratory studies of candidate addiction medications and nutritional interventions, genetic and pharmacologic modulators in neuroimaging, brain measures as predictors of medication and treatment response, and clinical trials testing novel medications for cocaine, opiate, nicotine, and marijuana addictions.

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37. Postdoctoral Fellow

Summary of Postdoctoral Fellowship:

Postdoctoral positions to study the molecular physiologies of InsP3R and MCU Ca2+ ion channels and CALHM ion channels are available in the laboratory of Kevin Foskett at the Perelman School of Medicine of the University of Pennsylvania in Philadelphia, Pennsylvania. Our focus is on the molecular physiologies of three ion channel families, and their roles in physiology, including bioenergetics, cancer, neurodegeneration and sensory perception. Our research on the IP3R Ca2+ release channel and the mitochondrial Ca2+ uniporter seeks to understand the molecular determinants and physiological functions of endoplasmic reticulum-to-mitochondria Ca2+ transfer. Our research on CALHM ion channels centers on their roles in taste perception and the elucidation of the functional roles of different CALHM family members. Projects are available to investigate many aspects of channel biophysics, Ca2+ signaling, structural biology, and animal models.

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38. Postdoctoral Fellow

Summary of Postdoctoral Fellowship:

Postdoctoral positions to study the molecular physiologies of InsP3R and MCU Ca2+ ion channels and CALHM ion channels are available in the laboratory of Kevin Foskett at the Perelman School of Medicine of the University of Pennsylvania in Philadelphia, Pennsylvania. Our focus is on the molecular physiologies of three ion channel families, and their roles in physiology, including bioenergetics, cancer, neurodegeneration and sensory perception. Our research on the IP3R Ca2+ release channel and the mitochondrial Ca2+ uniporter seeks to understand the molecular determinants and physiological functions of endoplasmic reticulum-to-mitochondria Ca2+ transfer. Our research on CALHM ion channels centers on their roles in taste perception and the elucidation of the functional roles of different CALHM family members. Projects are available to investigate many aspects of channel biophysics, Ca2+ signaling, structural biology, and animal models.

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39. Postdoc in computational and systems biology

Summary of Postdoctoral Fellowship:

The Tan research group is interdisciplinary and highly collaborative, utilizing both computational and experimental approaches to study gene regulation. We have pioneered multiple computational algorithms for regulatory genomics, epigenomics, and network biology. Specific projects will be defined by the candidates (and based on the candidates expertise) and with input from Dr. Tan and our close collaborators at the Center for Childhood Cancer Research CHOP and Abramson Cancer Center at the University of Pennsylvania. The postdoctoral fellow will be responsible for development of novel computational algorithms and/or experimental approaches to understand gene regulation in normal and cancer development.

Last Application Date: Open Until Filled

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40. Postdoctoral Fellow in iPSC Hematopoiesis Models

Summary of Postdoctoral Fellowship:

The Thom lab is an integrated team of computational and basic scientists studying genetic determinants of hematopoiesis (blood cell formation), with a focus on megakaryocyte and platelet development. We employ induced pluripotent stem cell (iPSC) and murine models to study hematopoietic development. We have an open postdoctoral fellowship position to study the role of tropomyosins during in vitro hematopoiesis. The ideal candidate will have a PhD, MD, or both, with experience using in vitro stem cell models. Additional experience with molecular biology, flow cytometry, genomics, and imaging modalities are an asset. Candidates should be willing to work in a team environment that is enthusiastic, collaborative, and supportive.

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41. Postdoc in single-cell cancer genomics

Summary of Postdoctoral Fellowship:

We are seeking a self-motivated and enthusiastic candidate for a postdoctoral scholar position. The postdoc will participate in an exciting project that uses various single-cell technologies to understand tumor clonal evolution, transcriptional and epigenetic heterogeneity and signaling within the tumor microenvironment, during standard and immuno therapeutic responses. The project is funded by a recent NCI center grant to establish the center for pediatric tumor cell atlas as part of the Moonshot initiative (https://humantumoratlas.org/). The project provides an excellent training opportunity in single cell biology and cancer biology.

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42. Postdoctoral Fellow in Neonatalogy/ Hematopoiesis

Summary of Postdoctoral Fellowship:

The Thom lab is an integrated team of computational and basic scientists studying genetic determinants of hematopoiesis (blood cell formation), with a focus on megakaryocyte and platelet development. We employ induced pluripotent stem cell (iPSC) and murine models to study hematopoietic development. We have an open postdoctoral fellowship position to study the role of actin regulatory molecules during murine hematopoiesis. The ideal candidate will have a PhD, MD, or both, with experience using in vivo murine models. Additional experience with molecular biology, flow cytometry, and imaging modalities are an asset. Candidates should be willing to work in a team environment that is enthusiastic, collaborative, and supportive.

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43. Postdoc –CRISPR screen in hematopoietic stem cells to study ribosome biogenesis /ubiquitin signaling

Summary of Postdoctoral Fellowship:

A postdoctoral fellow position is available at the University of Pennsylvania School of Medicine and the Children’s Hospital of Philadelphia, to perform state-of-the-art CRISPR/Cas9 screens to identify novel therapeutic targets for treating hematopoietic stem cell diseases. Hematopoietic stem cells give rise to all circulating blood cells throughout life. Maintenance of stem cell self-renewal, proliferation and differentiation is regulated by complex signaling pathways. Aberrant regulation leads to bone marrow failure or leukemia. Dr. Tong’s laboratory studies various signaling pathways in hematopoietic stem cells, bone marrow failure, and leukemia. Her laboratory recently identified a novel E3 ubiquitin ligase that plays a critical role in ribosome assembly and thereby controls hematopoietic stem cell regeneration.

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44. Postdoctoral Researcher in Bioinformatics and Computational Biology

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available at The Children’s Hospital of Philadelphia Research Institute. The successful candidate will be dedicated and motivated, have creative thinking skills and be a driver of her/his research. This is an exciting opportunity to work with a group of experts on computational genomics to improve algorithms and develop software tools for the long-read sequencing techniques. These technologies, such as Oxford Nanopore and Pacific BioSciences, have significant advantages over conventional short-read Illumina sequencing technologies. We are developing various deep neural network approaches to handle unique challenges in long-read sequencing data, to facilitate novel genetic discoveries and accelerate the implementation of precision medicine.

Last Application Date: Open Until Filled

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45. Postdoctoral Researcher in Genomics

Summary of Postdoctoral Fellowship:

A post-doctoral position in human genetics and genomics is immediately available. Research in our group focuses on the development of genomics and bioinformatics methods to analyze sequencing data, and to enable the implementation of genomic medicine in clinical settings. The successful candidate will work on developing novel genomic methods to study human diseases that are related to genomic repeats. Example projects include the use of Illumina sequencing, optical mapping or long-read sequencing to assay human genomes, transcriptomes and epigenomes from patients with undiagnosed diseases, and to understand how repetitive elements and structural variants in complex genomic regions cause human diseases.

Last Application Date: Open Until Filled

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46. Postdoctoral Fellowship Opening in Alzheimer’s Disease Genetics

Summary of Postdoctoral Fellowship:

We are seeking applications for postdoctoral researchers to work on any of the following areas: 1. Rare variant discovery in diverse, multi-ancestry datasets using genome-wide genotyping, whole-exome sequencing (WES), and whole-genome sequencing (WGS) data focusing on genome-wide association (GWA) analysis for identifying risk-increasing and protective variants for Alzheimer’s disease (AD), AD-Related Dementias (ADRDs) and other neurodegenerative diseases and disorders. This work will include developing and applying optimal analytic strategies accounting for global and local admixture in subjects of diverse ancestral backgrounds, and will benefit from experience with large datasets and cloud usage. 2. Algorithm development and analysis for quality control and association testing of whole-genome sequencing genotype data for AD, including processing and refining multi-allelic rare variant and X-chromosome variant data and identifying novel susceptibility loci for dementia

Last Application Date: Open Until Filled

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