29 Postdoctoral Fellowships at Karolinska Institute, Sweden

Are you holding PhD degree and looking for Postdoctoral Fellowships? Karolinska Institute, Sweden inviting application for multiple Postdoctoral Fellowships. Karolinska Institute is one of the largest university in the world with thousands of employees, students, and research scientists are involved in the innovation of science and technology daily.

Karolinska Institute has huge a campus in Sweden and widely known as for its contribution in top notch education and research. The contribution of Karolinska Institute is not only limited to natural sciences and engineering but it also offers high quality research as well as higher education in bio-medical sciences, social sciences, humanities, psychology, education, architecture etc..

1. Postdoctoral studies in systems biology of mRNA translation (scholarship)

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. The focus for the project will be to use biostatistics and bioinformatics to understand how mRNA translation is organized and orchestrated in health and disease.

Last Application Date: 05.May.2022

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2. Postdoctoral studies of mRNA translation in cancer

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. Although the focus for this project will be to use advanced molecular biology approaches to study mRNA translation in cancer, there will also be opportunities to learn analysis of large scale data sets.

Last Application Date: 05.May.2022

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3. Postdoctoral Researcher in Metabolic Engineering in RNA virus infection

Summary of Postdoctoral Fellowship:

Are you interested to learn how our immune system interacts with viruses and can we explore virus weakness to eliminate it? We are looking for a Post-Doctoral researcher for our research theme, the correlates of immune protection against RNA viruses, who will work mainly to understand the immune-metabolic modulation during acute or chronic viral infection. A major focus of the work will be on virus-host cell interaction and to determine the signaling pathways that drive virus-induced disease biology in HIV-1 and SARS-CoV-2. The ideal candidate will possess exceptional skills in virology, multi-color flow cytometry, and/or cell biology. Preference will be given to those who worked with the BSL3 viruses and immune modulation of cellular pathways in the cell lines and primary cells. Expertise in the field of metabolism, loss-of-function screens and reverse viral genetics including CRISPR-Cas9 would represent a major advantage.

Last Application Date: 30.Apr.2022

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4. Postdoctoral Researcher in NK cell biology

Summary of Postdoctoral Fellowship:

The Malmberg Lab is located in Stockholm/Sweden and Oslo/Norway and currently consists of 24 people. We are now looking for a highly motivated post-doc with an interest in molecular immunology and experimental immunotherapy. The project concerns the differentiation of human NK cells from inducible pluripotent stem cells (iPSC), with a particular focus on directed differentiation into effector cells with desired phenotype and function. One central element is to use our synthetic biology platform to improve the persistence and boost the cytotoxic potential of iPSC-derived NK cells. This project is carried out in close collaboration with our US-based industrial partner Fate Therapeutics and the Malmberg Lab at Oslo University Hospital.

Last Application Date: 30.Apr.2022

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5. Postdoctoral studies in Central Nervous System Regeneration after Spinal Cord Injury

Summary of Postdoctoral Fellowship:

Our lab investigates stromal scar formation and its impact on axonal regeneration and functional recovery following spinal cord injury. We discovered a new population of perivascular cells, called type A pericytes, as the source of fibrotic scar tissue (Göritz et al., Science, 2011) and identified pericyte-derived scar formation as a therapeutic target to achieve axonal regeneration and functional recovery following spinal cord injury (Dias et al., Cell, 2018). Recently, we showed that fibrotic scarring by perivascular cells is a conserved mechanism in the adult mammalian CNS (Dias et al., Nature Com., 2021). The intended project will test different strategies to interfere with fibrotic scarring to enhance axonal regeneration and functional recovery following spinal cord injury.

Last Application Date: 30.Apr.2022

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7. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (5)

Summary of Postdoctoral Fellowship:

We recently demonstrated that glutamine levels are lower in white adipocytes from obese compared to lean subjects and that this leads to white adipose tissue (WAT) inflammation (Petrus, Lecoutre et al, Cell Metabolism, 2020). Our new preliminary data in human and murine WAT, reveal that these changes are associated with decreased expression of Glutamine Synthase (GS, encoded by GLUL) and increased expression of glutaminase (GLS, encoded by GLS), the two enzymes governing glutamine metabolism. This suggests that glutamine turnover is a major determinant of adipocyte function. To further dissect the pathophysiological role of our observations in vivo, we have generated adipocyte-specific Gls and Glul knockout mice where we will study the effects of different perturbations on WAT and whole body metabolism. These analyses will be complemented by state-of-the-art mechanistic studies in human adipocytes in which we for instance will perform metabolic flux analyses following CRISPR/Cas9-mediated engineering of the glutamine pathway.

Last Application Date: 30.Apr.2022

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8. Postdoctoral Researcher in Metabolic Engineering in RNA virus infection

Summary of Postdoctoral Fellowship:

Are you interested to learn how our immune system interacts with viruses and can we explore virus weakness to eliminate it? We are looking for a Post-Doctoral researcher for our research theme, the correlates of immune protection against RNA viruses, who will work mainly to understand the immune-metabolic modulation during acute or chronic viral infection. A major focus of the work will be on virus-host cell interaction and to determine the signaling pathways that drive virus-induced disease biology in HIV-1 and SARS-CoV-2. The ideal candidate will possess exceptional skills in virology, multi-color flow cytometry, and/or cell biology.

Last Application Date: 30.Apr.2022

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9. Postdoctoral Researcher in NK cell biology

Summary of Postdoctoral Fellowship:

Our research group seeks to develop new strategies for cell-based immunotherapy based on insights into the functional regulation of NK cells. Through partnerships with leading NK cell groups in Europe and the US, as well as the biotech industry we design and run clinical trials for patients with cancer. At the Center for Infectious Medicine at the Karolinska Institutet you will find a stimulating research environment with the vision to be a world-leading translational research center within immunology.

Last Application Date: 30.Apr.2022

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10. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (1)

Summary of Postdoctoral Fellowship:

Many immune mediated diseases including type-I diabetes are linked to perturbed immune system development or skewed immune-microbiome relationships early in life. Most information on immune development to date stems from mouse models or cord blood, but neither of these can account for environmental exposures in human newborns. Our group has performed a first longitudinal study of immune development in human newborns using modern systems immunology methods and revealed immune-microbe differences with possible relevance to diseases such as type I diabetes. Microbial composition is influenced by mode of delivery, feeding and antibiotic exposure and the microbiome evolves through an ordered sequence of events.

Last Application Date: 30.Apr.2022

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11. Post doc position with a focus on host-microbe interplay in health and disease

Summary of Postdoctoral Fellowship:

The employment has a focus on research. The postdoctor will conduct research within several projects, focusing on the impact of host-microbiome interplay during immune homeostasis and dysregulation, using human data and data from experimental models. The main task of the postdoctor will be bioinformatics analysis of 16S and metagenomic data and their integration with environmental exposure data, clinical data and other OMICs layers.

Last Application Date: 20.Apr.2022

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12. Postdoctoral Researcher in RNA Biology

Summary of Postdoctoral Fellowship:

Dr. Linxian Li’s Laboratory has long interests in developing novel therapeutics for clinical applications. Committed to translating new technology for medical use, the Li group focuses on using chemical synthesis, biological tools and artificial intelligence to develop mRNA therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in RNA biology.

Last Application Date: 24.Apr.2022

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13. Postdoctoral Researcher in Enzyme Engineering

Summary of Postdoctoral Fellowship:

Dr. Linxian Li’s Laboratory has long interests in developing novel therapeutics for clinical applications. Committed to translating new technology for medical use, the Li group focuses on using chemical synthesis, biological tools and artificial intelligence to develop mRNA therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in enzyme engineering.

Last Application Date: 24.Apr.2022

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14. Postdoctoral fellow in projects on person-centered care transition after stroke

Summary of Postdoctoral Fellowship:

We are looking for a postdoctoral fellow who will work on a project on person-centered care transition after stroke and TIA. The project is called Missing link and is based on the research group Neuroepidemiology and health care research. The project aims to evaluate a newly developed care transition where the patient should feel safe, involved and well-informed through the care transition in connection with discharge from hospital after stroke and TIA. The project is a collaboration between people with stroke, health and medical staff and an interdisciplinary project group of researchers at Karolinska Institutet. The group includes physiotherapists, sociologists, nurses, doctors and pharmacists. The project team is currently conducting a feasibility study to evaluate the feasibility of the intervention.

Last Application Date: 2022-04-26

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15. SRP Diabetes Postdoctoral Fellowship Programme at Karolinska Institutet

Summary of Postdoctoral Fellowship:

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project, mentored by world-leading researchers in the field of diabetes. To increase coherence around the Fellowship programme, several events will be held throughout the year such as high-profile lectures, symposia, etc. which the fellows will attend. The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2022, though some flexibility with the start date might be possible.

Last Application Date: 30.Apr.2022

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16. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (2)

Summary of Postdoctoral Fellowship:

We are interested in understanding how skeletal muscle insulin sensitivity is altered, both in response to pathology such as type diabetes, and as a response to physical exercise. This fellowship programme is focused on the role of miRNAs in this regard, in particular miRNAs in small extracellular vesicles (also called exosomes. We have previously identified several miRNA which are dysregulated in skeletal muscle in subjects with type 2 diabetes, and which contribute to changes in metabolism and insulin signalling, including let7 (Jiang et al., 2013), miR-29 (Massart et al., 2017) and mIR20b (Katayama et al., 2018). Since miRNAs are able to target multiple genes simultaneously, miRNAs provide a potential mechanism for efficiently modulating a whole pathway to change or alter the functional properties in specific target tissues.

Last Application Date: 30.Apr.2022

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17. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (3)

Summary of Postdoctoral Fellowship:

Comorbidities of type II diabetes (T2D) are major health concerns worldwide, including peripheral artery disease (PAD). PAD lowers blood flow to the lower limb, causing muscle ischemia and dysfunction and reduced exercise tolerance. Functionality of limb skeletal muscle is a key component for determining morbidity and mortality risk in patients with PAD. Interventions that improve distal arterial pressures (ie. bypass surgery) generally fail to normalize the structural and functional abnormalities of muscles, which point towards pathophysiological mechanisms inside the skeletal myofibers that reduce overall muscle function. Despite serious muscle abnormalities, the field is lacking molecular understanding of PAD-induced muscle dysfunction.

Last Application Date: 30.Apr.2022

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18. Postdoctoral Researcher/The Strategic Research Programme for Diabetes (4)

Summary of Postdoctoral Fellowship:

The postdoctoral project will focus on pharmacoepidemiological research and causal inference methods using data from national health, population and quality registers. The aim is to investigate the impact of socioeconomic factors on antidiabetic medications (ADM) use, discontinuation and type 2 diabetes (T2D) consequences such as cardiovascular diseases, kidney failure and retinopathy. The overarching purpose of the project is to identify differences in patterns of ADM use across socioeconomic groups, which will ultimately provide evidence for the development of targeted interventions for treatment management and guidelines increasing awareness about high-risk groups among the vulnerable population of T2D patients.

Last Application Date: 30.Apr.2022

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19. Postdoctoral studies Targeting the Ubiquitin-Proteasome System with Small Molecules

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated and skilled scientist with experience in drug development and/or the ubiquitin-proteasome system or autophagy. Advanced skills in molecular biology, cell biology and biochemistry are important assets for this project. A background in chemistry and/or bioinformatic analysis can also be advantageous. Other helpful skills are experience with the cell-based assays and fluorescence microscopy. Good knowledge of both spoken and written English is a requirement.

Last Application Date: 30.Apr.2022

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20. Postdoctoral fellow with a focus on risk assessment of chemicals

Summary of Postdoctoral Fellowship:

We are looking for a motivated Postdoctoral fellow who has a doctorate in regulatory toxicology or related disciplines. You will work with great independence in project form together with other researchers at the unit for integrative toxicology. You are responsible for developing the work with dose-response analysis in relation to data from a number of different studies – from experimental models (in vitro and in vivo) to epidemiology. You present the results in the form of scientific articles and at conferences, but you are also a driving force in building a network of contacts at Swedish and international authorities and contribute to the unit’s teaching activities.

Last Application Date: 2022-04-08

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21. Postdoc Researcher in Translational Melanoma Research

Summary of Postdoctoral Fellowship:

We are looking for a postdoc who is curious and eager to solve biological questions with focus on translational melanoma research. Specifically, we are interested in understanding how the inflammatory response in the tumor microenvironment affects tumor progression and response to melanoma therapies. The current position offers outstanding opportunities to develop as a researcher in an innovative and stimulating research environment by combining, together with a dedicated group of scientists and clinicians where the postdoc will contribute with her/his expertise.

Last Application Date: 11.Apr.2022

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22. Postdoctoral Researcher in protein biochemistry and biotechnology

Summary of Postdoctoral Fellowship:

This project is focused on protein engineering and recombinant expression and purification of silk proteins, and functionalized variants thereof, in prokaryotic hosts, with subsequent biochemical and biophysical characterization. You will formulate different materials and do mechanical, structural and functional characterization of these. The successful candidate is expected to have a large interest in biotechnology and protein biochemistry and is expected to enjoy practical lab work and independently generate and analyze data. The candidate will supervise doctorial students and master students in the lab. We work in collaboration with other groups and very interdisciplinary, which demands the applicant to be independent, creative, have a positive attitude and be collaborative. The candidate will work primarily at KI campus Flemingsberg, but is also expected to travel to and work in the lab at SLU in Uppsala.

Last Application Date: 12.Apr.2022

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23. ONE Postdoctoral Researcher in chemical and genetic screens

Summary of Postdoctoral Fellowship:

We are currently looking for a postdoctoral scientist to join our team with a Ph.D. in Cell Biology, Molecular Biology, Biochemistry, or other relevant fields. We are specifically looking for a highly motivated scientist that is looking to complement his/her skills with experience in large chemical and genetic screens, and that has the capacity to independently develop a scientific research project that relies mostly on cell and molecular biology technologies. In addition, it is expected that the candidate will help in the training of junior group members. Other valuable skills such as writing or presenting capacities or social skills will also be appreciated.

Last Application Date: 13.Apr.2022

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24. Postdoctoral researcher in skeletal stem cells

Summary of Postdoctoral Fellowship:

This opening is focused on skeletal growth and the mechanisms of its maintenance. The successful candidate will be expected to plan and conduct experimental research to reveal basic mechanisms relating to skeletal disorders arising from childhood cancer treatments. More specifically, duties will include collecting and analysing human tissues, maintaining a colony of mice, processing and analysing murine samples. Methodologies include confocal microscopy, histological and histochemical staining, immunofluoresence, in situ hybridisation and RNAseq. The candidate is expected to drive their project forward and actively follow the scientific literature.

Last Application Date: 14.Apr.2022

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25. Postdoctoral Researcher in project focused on dopamine neuron maintenance in Parkinson’s disease

Summary of Postdoctoral Fellowship:

The lab’s focus is on the development and maintenance of dopamine neurons within the ventral midbrain. We are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have relevance for regenerative medicine and neurodegeneration in relation to Parkinson’s disease and other brain disorders. We are using mouse genetics and other methods including single cell RNA sequencing in our studies. In collaborative projects we also focus on regenerative strategies such as stem cell therapy, and on the maintenance of dopamine neurons in the human brain.

Last Application Date: 14.Apr.2022

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26. Postdoctoral Researcher in Molecular and Translation Lung Cancer Research

Summary of Postdoctoral Fellowship:

We are seeking a Postdoctoral Researcher (Scholarship) with an interest in lung cancer biology/therapy. You should hold great prior knowledge in tumor biology and it is preferred that you already are familiar with extracellular vesicles (EVs) research. When joining us you will work in a multidisciplinary environment, close to frontline preclinical/translational/clinical lung cancer research but also in context of radiation therapy as well as with our partners on microchip technology for EVs characterization.

Last Application Date: 15.Apr.2022

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27. Postdoctoral researcher to study synergistic effects between DNA damaging cancer therapeutics and targeted agents for an industrial collaboration

Summary of Postdoctoral Fellowship:

Cancer is often characterized by genome instability which is one of the enabling characteristics of cancer. Along the progression of cancer, mutations occurring in the genome maintenance and surveillance systems endanger the integrity of the genome. This genome instability results in new mutations and genomic rearrangements driving cancer progression via selection of favourable phenotypes. However, genomic instable cancer cells are more vulnerable to DNA damage than non-malignant cells since their DNA repair machinery often is deficient. This cancer cell vulnerability, along with the high proliferation rate of cancer cells, enables the usage of DNA damaging cancer treatment, such as ionizing radiation and chemotherapy, which have been used in cancer treatment for nearly a century.

Last Application Date: 18.Apr.2022

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28. Postdoctoral Researcher in Risk and Resilience in Neurodevelopmental Conditions using the ICF system

Summary of Postdoctoral Fellowship:

We are seeking a postdoctoral researcher with a strong passion for conducting research that strives to contribute to the quality of life and mental wellbeing of individuals with Neurodevelopmental Conditions. As part of a European consortium – Risk and Resilience in Developmental Diversity and Mental Health (R2D2-MH) – we are conducting research which aims to improve the mental health outcomes of young people with these challenges. The postdoctoral position will examine the factors related to risk and resilience for adverse health and psychosocial outcomes in by developing International of Classification of Functioning (ICF) core sets for risk and resilience in this population. In addition, the postdoc interacts with researchers in the European Consortium and contributes to other work packages investigating resilience.

Last Application Date: 18.Apr.2022

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29. Postdoctor in Immunology

Summary of Postdoctoral Fellowship:

A postdoctoral research position is now available in the laboratory of Immunology and Oncology led by Dr Lisa Westerberg. The laboratory is located in the top modern Biomedicum building with shared infrastructure for advanced technology platforms and built for interdisciplinary collaborations. Ongoing research is focused on understanding the molecular mechanisms in development of immunodeficiency diseases with high incidence of autoimmunity and cancer.

Last Application Date: 19.Apr.2022

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